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NDUFS7 Antibody (BS-11734R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse skeletal muscle; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with NDUFS7 Polyclonal Antibody, Unconjugated (bs-11734R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody ... View More
Product Details
BS-11734R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human NDUFS7, amino acids 101-160.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CI-20kD; complex I 20kDa subunit; complex I, mitochondrial respiratory chain, 20-KD subunit; Complex I-20kD; FLJ45860; FLJ46880; MGC120002; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 20 kDa subunit; NADH-ubiquinone oxidoreductase Fe-S protein 7; NADH:ubiquinone oxidoreductase PSST subunit; PSST subunit
Gene Aliases: 1010001M04Rik; CI-20; CI-20KD; MY017; NDUFS7; PSST
UniProt ID: (Human) O75251, (Mouse) Q9DC70
Entrez Gene ID: (Human) 374291, (Mouse) 75406, (Rat) 362837
protease binding
NADH dehydrogenase activity
protein binding
NADH dehydrogenase (ubiquinone) activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
metal ion binding
quinone binding
4 iron, 4 sulfur cluster binding
oxidoreductase activity
iron-sulfur cluster binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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