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Proteintech
NEIL1 Monoclonal Antibody (1C6D6)
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Product Details
67012-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1C6D6
Immunogen
NEIL1 Fusion Protein Ag8307
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA endonuclease eight-like glycosylase 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease 8-like 1; endonuclease VIII; Endonuclease VIII-like 1; FLJ22402; FPG1; NEH1; nei endonuclease VIII-like 1; Nei homolog 1; nei-like DNA glycosylase 1; Nei-like protein 1
Gene Aliases: 2810450N13Rik; FPG1; hFPG1; NEI1; NEIL1
UniProt ID: (Human) Q96FI4, (Mouse) Q8K4Q6
Entrez Gene ID: (Human) 79661, (Mouse) 72774
damaged DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
protein C-terminus binding
zinc ion binding
hydrolase activity, acting on glycosyl bonds
DNA N-glycosylase activity
purine-specific mismatch base pair DNA N-glycosylase activity
nucleic acid binding
DNA binding
catalytic activity
uracil DNA N-glycosylase activity
hydrolase activity
hydrolase activity, hydrolyzing N-glycosyl compounds
lyase activity
single-strand selective uracil DNA N-glycosylase activity
DNA-3-methylbase glycosylase activity
nicotinamide riboside hydrolase activity
nicotinic acid riboside hydrolase activity
deoxyribonucleoside 5'-monophosphate N-glycosidase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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