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Proteintech
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Immunogen sequence: MLKFQEAAK CVSGSTAIST YPKTLIARRY VLQQKLGSGS FGTVYLVSDK KAKRGEELKV LKEISVGELN PNETVQANLE AQLLSKLDHP AIVKFHASFV EQDNFCIITE YCEGRDLDDK IQEYKQAGKI FPENQIIEWF IQLLLGVDYM HERRILHRDL KSKNVFLKNN LLKIGDFGVS RLLMGSCDLA TTLTGTPHYM SPEALKHQGY DTKSDIWSLA CILYEMCCMN HAFAGSNFLS IVLKIVEGDT PSLPERYPKE LNAIMESMLN KNPSLRPSAI EILKIPYLDE QLQNLMCRYS E (1-300 aa encoded by BC028587)
NEK11 (FLJ23495) belongs to the NIMA family of kinases which are involved in DNA replication and genotoxic stress response. NEK11 encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: nek11; Never in mitosis A-related kinase 11; NIMA (never in mitosis gene a)- related kinase 11; NIMA (never in mitosis gene a)-related expressed kinase 11; NIMA-related kinase 11; NimA-related protein kinase 11; Serine/threonine-protein kinase Nek11
Gene Aliases: 4932416N14Rik; NEK11
UniProt ID: (Human) Q8NG66, (Mouse) Q8C0Q4
Entrez Gene ID: (Human) 79858, (Rat) 315978, (Mouse) 208583
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