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Product Details
H00004758-M01
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3F9
Immunogen
NEU1 (NP_000425, 334 a.a. approximately 415 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: NPAHPEFRVN LTLRWSFSNG TSWRKETVQL WPGPSGYSSL ATLEGSMDGE EQAPQLYVLY EKGRNHYTES ISVAKISVYG TL
Target Information
NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetylneuraminyl hydrolase; EC 3.2.1.18; exo-alpha-sialidase; FLJ93471; G9 sialidase; HLA-B-associated transcript 7; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; sialidase 1; sialidase 1 (lysosomal sialidase); Sialidase-1
Gene Aliases: AA407268; AA407316; Aglp; Apl; Bat-7; Bat7; G9; Map-2; NANH; NEU; Neu-1; NEU1; SIAL1
UniProt ID: (Human) Q99519, (Mouse) O35657
Entrez Gene ID: (Human) 4758, (Mouse) 18010, (Rat) 24591
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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