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Product Details
14610-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NEUROD4 Fusion Protein Ag6183 (77-331 aa encoded by BC040961)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTKARLERF RARRVKANAR ERTRMHGLND ALDNLRRVMP CYSKTQKLSK IETLRLARNY IWALSEVLET GQTPEGKGFV EMLCKGLSQP TSNLVAGCLQ LGPQSVLLEK HEDKSPICDS AISVHNFNYQ SPGLPSPPYG HMETHLLHLK PQVFKSLGES SFGSHLPDCS TPPYEGPLTP PLSISGNFSL KQDGSPDLEK SYSFMPHYPS SSLSSGHVHS TPFQAGTPRY DVPIDMSYDS YPHHGIGTQL NTVFTE (77-331 aa encoded by BC040961)
Target Information
Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATH-3; atonal homolog 3; bHLHa4; Class A basic helix-loop-helix protein 4; Helix-loop-helix protein mATH-3; mATH3; NeuroD4; neurogenic differentiation 4; Neurogenic differentiation factor 4; Protein atonal homolog 3
Gene Aliases: AI846749; ATH-3; ATH3; ATOH3; BHLHA4; MATH-3; MATH3; NEUROD4
UniProt ID: (Human) Q9HD90, (Mouse) O09105
Entrez Gene ID: (Human) 58158, (Mouse) 11923, (Rat) 288821
neuron migration
transcription, DNA-templated
regulation of transcription, DNA-templated
Notch signaling pathway
multicellular organism development
nervous system development
neuroblast proliferation
glial cell differentiation
cell differentiation
amacrine cell differentiation
camera-type eye development
cell fate commitment
positive regulation of cell differentiation
neuron development
retina development in camera-type eye
Performance Guarantee
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