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NFE2L1 Antibody (PA5-114765) in IHC (P)
Immunohistochemistry analysis of NFE2L1 in human colorectal cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114765) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-114765
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NFE2L1(Accession Q14494), corresponding to amino acid residues E99-F149.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899401
Product Specific Information
Antibody detects endogenous levels of total NFE2L1.
Target Information
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoplasmic reticulum membrane sensor NFE2L1; LCR-F1; Locus control region-factor 1; NF-E2-related factor 1; NFE2-related factor 1; nuclear factor (erythroid-derived 2)-like 1; Nuclear factor erythroid 2-related factor 1; nuclear factor, erythroid 2-like 1; Nuclear factor, erythroid derived 2, like 1; Protein NRF1, p120 form; TCF-11; transc; Transcription factor 11; transcription factor 11 (basic leucine zipper type); transcription factor HBZ17; transcription factor LCR-F1
Gene Aliases: AA408798; AW212678; HBZ17; LCR-F1; Lcrf1; NFE2L1; NRF1; TCF-11; TCF11
UniProt ID: (Human) Q14494, (Mouse) Q61985
Entrez Gene ID: (Human) 4779, (Mouse) 18023
transcription regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
protein binding
DNA binding
sequence-specific DNA binding
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
heme biosynthetic process
inflammatory response
anatomical structure morphogenesis
erythrocyte differentiation
cellular response to oxidative stress
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
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