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Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRTRLYLNLG LTFESLQQTA LCNDYFRKSI FLAEQNHLYE DLFRARYNLG TIHWRAGQHS QAMRCLEGAR ECAHTMRKRF MESECCVVIA QVLQDLGDFL AAKRALKKAY RLGSQKPVQR AAICQNLQHV LAVVRLQQQL EEAEGRDPQG AMVICEQLGD LFSKAGDFPR AAEAYQKQLR FAELLDRPGA ERAIIHVSLA TTLGDMKDHH GAVRHYEEEL RLRSGNVLEE AKTWLNIALS REEAGDAYEL LAPCFQKALS CAQQAQRPQL QRQVLQHLHT VQLRLQPQEA PETETRLREL SVAEDEDEEE EAEEAAATAE SEALEAGEVE LSEGEDDTDG LTPQLEEDEE LQGHLGRRKG SKWNRRNDMG ETLLHRACIE GQLRRVQDLV RQGHPLNPRD YCGWTPLHEA CNYGHLEIVR FLLDHGAAVD DPGGQGCEGI TPLHDALNCG HFEVAELLLE RGASVTLRTR KGLSPLETLQ QWVKLYRRDL DLETRQKARA MEMLLQAAAS GQDPHSSQAF HTPSSLLFDP ETSPPLSPCP EPPSNSTRLP EASQVHVRVS PGQAAPAMAR PRRSRHGPAS SSSSSEGEDS AGPARPSQKR PRCSATAQRV AAWTPGPASN REAATASTSR AAYQAAIRGV GSAQSRLGPG PPRGHSKALA PQAALIPEEE CLAGDWLELD MPLTRSRRPR PRGTGDNRRP SSTSGSDSEE SRPRARAKQV RLTCMQSCSA PVNAGPSSLA SEPPGSPSTP RVSEPSGDSS AAGQPLGPAP PPPIRVRVQV QDHLFLIPVP HSSDTHSVAW LAEQAAQRYY QTCGLLPRLT LRKEGALLAP QDLIPDVLQS NDEVLAEVTS WDLPPLTDRY RRACQSLGQG EHQQVLQAVE LQGLGLSFSA CSLALDQAQL TPLLRALKLH TALRELRLAG NRLGDKCVAE LVAALGTMPS LALLDLSSNH LGPEGLRQLA MGLPGQATLQ SLEELDLSMN PLGDGCGQSL ASLLHACPLL STLRLQACGF GPSFFLSHQT ALGSAFQDAE HLKTLSLSYN ALGAPALART LQSLPAGTLL HLELSSVAAG KGDSDLMEPV FRYLAKEGCA LAHLTLSANH LGDKAVRDLC RCLSLCPSLI SLDLSANPEI SCASLEELLS TLQKRPQGLS FLGLSGCAVQ GPLGLGLWDK IAAQLRELQL CSRRLCAEDR DALRQLQPSR PGPGECTLDH GSKLFFRRL
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA repair protein; I-kappa-B-related protein; ikappaBR; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; tonsoku-like; Tonsoku-like protein
Gene Aliases: IKBR; NFKBIL2; TONSL
UniProt ID: (Human) Q96HA7
Entrez Gene ID: (Human) 4796
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