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FIGURE: 1 / 1
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Mouse (83%), Rat (82%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA repair protein; I-kappa-B-related protein; ikappaBR; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; tonsoku-like; Tonsoku-like protein
Gene Aliases: IKBR; NFKBIL2; TONSL
UniProt ID: (Human) Q96HA7
Entrez Gene ID: (Human) 4796
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