Proteintech

NFKBIZ Polyclonal Antibody

NFKBIZ Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 4

NFKBIZ Antibody (14014-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 14014-1-AP (NFKBIZ antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

14014-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NFKBIZ Fusion Protein Ag5120 (369-718 aa encoded by BC060800)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.31 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: AHLHSFSMM PSSACEAMVG HEMASDSSNT SLPFSNMGNP MNTTQLGKSL FQWQVEQEES KLANISQDQF LSKDADGDTF LHIAVAQGRR ALSYVLARKM NALHMLDIKE HNGQSAFQVA VAANQHLIVQ DLVNIGAQVN TTDCWGRTPL HVCAEKGHSQ VLQAIQKGAV GSNQFVDLEA TNYDGLTPLH CAVIAHNAVV HELQRNQQPH SPEVQELLLK NKSLVDTIKC LIQMGAAVEA KDRKSGRTAL HLAAEEANLE LIRLFLELPS CLSFVNAKAY NGNTALHVAA SLQYRLTQLD AVRLLMRKGA DPSTRNLENE QPVHLVPDGP VGEQIRRILK GKSIQQRAPP Y (369-718 aa encoded by BC060800)

Target Information

I-kappa-B-zeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein that is highly homologous to the IkappaB family member Bcl-3. Transcription of IkappaBzeta is upregulated by stimulation with TLR ligands, IL-1 and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65 and recombinant IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Single-Cell Transcriptome Analysis of Chronic Antibody-Mediated Rejection After Renal Transplantation.

Frontiers in immunology

Kong F,Ye S,Zhong Z,Zhou X,Zhou W,Liu Z,Lan J,Xiong Y,Ye Q

Wed Feb 23 00:00:00 UTC 2022

The negative feedback loop of NF-κB/miR-376b/NFKBIZ in septic acute kidney injury.

JCI insight

Liu Z,Tang C,He L,Yang D,Cai J,Zhu J,Shu S,Liu Y,Yin L,Chen G,Liu Y,Zhang D,Dong Z

Thu Dec 17 00:00:00 UTC 2020

Silencing NUDT21 Attenuates the Mesenchymal Identity of Glioblastoma Cells via the NF-κB Pathway.

Frontiers in molecular neuroscience

Lou JC,Lan YL,Gao JX,Ma BB,Yang T,Yuan ZB,Zhang HQ,Zhu TZ,Pan N,Leng S,Song GJ,Zhang B

Mon Mar 21 00:00:00 UTC 2022

Silencing NUDT21 Attenuates the Mesenchymal Identity of Glioblastoma Cells via the NF-κB Pathway.

Frontiers in molecular neuroscience

Lou JC,Lan YL,Gao JX,Ma BB,Yang T,Yuan ZB,Zhang HQ,Zhu TZ,Pan N,Leng S,Song GJ,Zhang B

Mon Mar 21 00:00:00 UTC 2022

Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.

International journal of biological macromolecules

Xu D,Wang H,Zheng W,Gao Y,Wang M,Zhang Y,Gao Q

Tue Nov 01 00:00:00 UTC 2016

Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.

International journal of biological macromolecules

Xu D,Wang H,Zheng W,Gao Y,Wang M,Zhang Y,Gao Q

Tue Nov 01 00:00:00 UTC 2016

Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.

The Journal of surgical research

Zhang Y,Li R,Zhu J,Wang Z,Lv S,Xiong JY

Thu Jan 01 00:00:00 UTC 2015

Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.

The Journal of surgical research

Zhang Y,Li R,Zhu J,Wang Z,Lv S,Xiong JY

Thu Jan 01 00:00:00 UTC 2015

Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.

Toxicology and applied pharmacology

Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y

Wed Oct 15 00:00:00 UTC 2014

Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.

Toxicology and applied pharmacology

Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y

Wed Oct 15 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: FLJ30225; FLJ34463; I-kappa-B-zeta; Ikappa B-zeta variant 3; IkappaB-zeta; ikappaBzeta; IkB-zeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; MAIL; Molecule possessing ankyrin repeats induced by lipopolysaccharide; molecule possessing ankyrin-repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; OTTHUMP00000214340

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Gene Aliases: AA408868; IKBZ; INAP; MAIL; NFKBIZ; RGD1310834

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UniProt ID: (Human) Q9BYH8, (Mouse) Q9EST8

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Entrez Gene ID: (Human) 64332, (Rat) 304005, (Mouse) 80859

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Function(s)

transcription cofactor activity protein binding

Process(es)

regulation of transcription from RNA polymerase II promoter inflammatory response transcription, DNA-templated regulation of transcription, DNA-templated

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NFKBIZ Polyclonal Antibody

NFKBIZ Antibody (14014-1-AP) in ICC/IF

Product Details

14014-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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