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Proteintech
NFU1 Polyclonal Antibody
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Product Details
25598-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NFU1 Fusion Protein Ag22343 (1-254 aa encoded by BC113692)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAATARRGW GAAAVAAGLR RRFCHMLKNP YTIKKQPLHQ FVQRPLFPLP AAFYHPVRYM FIQTQDTPNP NSLKFIPGKP VLETRTMDFP TPAAAFRSPL ARQLFRIEGV KSVFFGPDFI TVTKENEELD WNLLKPDIYA TIMDFFASGL PLVTEETPSG EAGSEEDDEV VAMIKELLDT RIRPTVQEDG GDVIYKGFED GIVQLKLQGS CTSCPSSIIT LKNGIQNMLQ FYIPEVEGVE QVMDDESDEK EANSP (1-254 aa encoded by BC113692)
Target Information
This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HIRA-interacting protein 5; histone cell cycle regulation defective interacting protein 5; iron-sulfur cluster scaffold protein; mHIRIP5; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial; NifU-like C-terminal domain containing
Gene Aliases: 0610006G17Rik; CGI-33; HIRIP; HIRIP5; MMDS1; Nfu; NFU1; NifU; NIFUC
UniProt ID: (Human) Q9UMS0, (Mouse) Q9QZ23
Entrez Gene ID: (Human) 27247, (Rat) 297416, (Mouse) 56748
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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