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Invitrogen
NGAL Polyclonal Antibody
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NGAL Antibody (PA5-46916) in IHC (F)
Immunohistochemical analysis of NGAL in perfusion fixed frozen sections of mouse mammary gland. Samples were incubated with NGAL polyclonal antibody (Product # PA5-46916) using a dilution of 3 µg/mL for 1 hour at room temperature followed by Anti-Goat IgG VisUCyte™ HRP Polymer Antibody. Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to extrac... View More
Product Details
PA5-46916
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Lipocalin-2/NGAL Gln21-Asn200
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609490
Product Specific Information
In direct ELISAs, approximately 50% cross-reactivity with recombinant rat Lipocalin-2/NGAL is observed, approximately 10% cross-reactivity with recombinant human (rh) Lipocalin-2/NGAL is observed, and less than 5% cross-reactivity with rhLipocalin-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 24p3; HGNC:6526; Lipocalin-2; Lipocalin2; Neutrophil gelatinase-associated lipocalin; NGAL; Oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin LCN2; SV-40-induced 24P3 protein; uterocalin
Gene Aliases: 24p3; AW212229; Lcn2; Sip24
UniProt ID: (Mouse) P11672
Entrez Gene ID: (Mouse) 16819
immune system process
transport
ion transport
apoptotic process
response to virus
response to herbicide
positive regulation of gene expression
siderophore transport
positive regulation of cell projection organization
response to drug
innate immune response
iron ion homeostasis
protein homotrimerization
cellular response to hydrogen peroxide
extrinsic apoptotic signaling pathway in absence of ligand
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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