Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Immunogen sequence: MAAAALGSSS GSASPAVAEL CQNTPETFLE ASKLLLTYAD NILRNPNDEK YRSIRIGNTA FSTRLLPVRG AVECLFEMGF EEGETHLIFP KKASVEQLQK IRDLIAIERS SRLDGSNKSH KVKSSQQPAA STQLPTTPSS NPSGLNQHTR NRQGQSSDPP SASTVAADSA ILEVLQSNIQ HVLVYENPAL QEKALACIPV QELKRKSQEK LSRARKLDKG INISDEDFLL LELLHWFKEE FFHWVNNVLC SKCGGQTRSR DRSLLPSDDE LKWGAKEVED HYCDACQFSN RFPRYNNPEK
This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hPNGase; mPNGase; N-glycanase 1; peptide N-glycanase homolog; Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Peptide:N-glycanase; PNGase
Gene Aliases: 1110002C09Rik; CDDG; CDG1V; NGLY1; PNG1; PNGase
UniProt ID: (Human) Q96IV0, (Rat) Q5XI55, (Mouse) Q9JI78
Entrez Gene ID: (Human) 55768, (Rat) 361014, (Mouse) 59007
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