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NIPBL Polyclonal Antibody

NIPBL Antibody in Immunocytochemistry (ICC/IF)

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NIPBL Antibody (18792-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 18792-1-AP (NIPBL antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

18792-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:50-1:500

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NIPBL Fusion Protein Ag5663 (2523-2686 aa encoded by BC033847)

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MKCLPENSA PLIEFANVSQ GILLLLMLKQ HLKNLCGFSD SKIQKYSPSE SAKVYDKAIN RKTGVHFHPK QTLDFLRSDM ANSKITEEVK RSIVKQYLDF KLLMEHLDPD EEEEEGEVSA STNARNKAIT SLLGGGSPKN NTAAETEDDE SDGEDRGGGT SGVRRRRSQR ISQRIT (2523-2686 aa encoded by BC033847)

Target Information

Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation.

Nature communications

Liu D,Zhang XX,Li MC,Cao CH,Wan DY,Xi BX,Tan JH,Wang J,Yang ZY,Feng XX,Ye F,Chen G,Wu P,Xi L,Wang H,Zhou JF,Feng ZH,Ma D,Gao QL

Mon Apr 30 00:00:00 UTC 2018

C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation.

Nature communications

Liu D,Zhang XX,Li MC,Cao CH,Wan DY,Xi BX,Tan JH,Wang J,Yang ZY,Feng XX,Ye F,Chen G,Wu P,Xi L,Wang H,Zhou JF,Feng ZH,Ma D,Gao QL

Mon Apr 30 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: Delangin; Delangin homolog; DKFZp434L1319; FLJ11203; FLJ12597; FLJ13354; FLJ13648; Nipped-B homolog; Nipped-B-like protein; SCC2 homolog; sister chromatid cohesion 2 homolog

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Gene Aliases: CDLS; CDLS1; IDN3; IDN3-B; NIPBL; SCC2

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UniProt ID: (Human) Q6KC79, (Mouse) Q6KCD5

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Entrez Gene ID: (Human) 25836, (Mouse) 71175, (Rat) 294787

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Function(s)

chromatin binding protein binding protein C-terminus binding mediator complex binding histone deacetylase binding protein N-terminus binding chromo shadow domain binding molecular_function

Process(es)

negative regulation of transcription from RNA polymerase II promoter metanephros development heart morphogenesis outflow tract morphogenesis cellular response to DNA damage stimulus mitotic sister chromatid cohesion brain development sensory perception of sound stem cell population maintenance positive regulation of histone deacetylation maintenance of mitotic sister chromatid cohesion cellular protein localization embryonic forelimb morphogenesis forelimb morphogenesis external genitalia morphogenesis positive regulation of multicellular organism growth ear morphogenesis regulation of hair cycle fat cell differentiation positive regulation of ossification negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of embryonic development embryonic digestive tract morphogenesis developmental growth eye morphogenesis regulation of developmental growth embryonic viscerocranium morphogenesis cognition face morphogenesis gall bladder development uterus morphogenesis cellular response to X-ray cell cycle heart development embryonic cranial skeleton morphogenesis biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NIPBL Polyclonal Antibody

NIPBL Antibody (18792-1-AP) in ICC/IF

Product Details

18792-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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