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Abnova
NKD1 Polyclonal Antibody, MaxPab™
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Product Details
H00085407-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NKD1 (NP_149110.1, 1 a.a. approximately 470 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGKLHSKPAA VCKRRESPEG DSFAVSAAWA RKGIEEWIGR QRCPGGVSGP RQLRLAGTIG RSTRELVGDV LRDTLSEEEE DDFRLEVALP PEKTDGLGSG DEKKMERVSE PCPGSKKQLK FEELQCDVSM EEDSRQEWTF TLYDFDNNGK VTREDITSLL HTIYEVVDSS VNHSPTSSKM LRVKLTVAPD GSQSKRSVLV NQADLQSARP RAETKPTEDL RSWEKKQRAP LRFQGDSRLE QSGCYHHCVD ENIERRNHYL DLAGIENYTS QFGPGSPSVA QKSELPPRTS NPTRSRSHEP EAIHIPHRKP QGVDPASFHF LDTPIAKVSE LQQRLRGTQD GSKHFVRSPK AQGKSVGVGH VARGARNKPP LGPAIPAVSP SAHLAASPAL LPSLAPLGHK KHKHRAKESQ QGCRGLQAPL ASGGPVLGRE HLRELPALVV YESQAGQPVQ RHEHHHHHEH HHHYHHFYQT
Target Information
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin-Tcf signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dvl-binding protein; hNkd; hNkd1; naked cuticle-1; Naked-1; Protein naked cuticle homolog 1
Gene Aliases: Naked1; NKD; NKD1; PP7246
UniProt ID: (Human) Q969G9
Entrez Gene ID: (Human) 85407
eye photoreceptor cell differentiation
somatic muscle development
Wnt signaling pathway
positive regulation of protein catabolic process
negative regulation of canonical Wnt signaling pathway
regulation of cell motility involved in somitogenic axis elongation
positive regulation of non-canonical Wnt signaling pathway via JNK cascade
negative regulation of convergent extension involved in axis elongation
positive regulation of Wnt signaling pathway, planar cell polarity pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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