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          • Primary Antibodies ›
          • NKG2A/B/C/E/F Antibodies

          Bioss

          NKG2A/B + NKG2C + NKG2E + NKG2F Polyclonal Antibody

          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite NKG2A/B + NKG2C + NKG2E + NKG2F Polyclonal Antibody

          Product Details

          BS-2416R

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          Flow Cytometry (Flow)

          5 µg/test
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Non-human primate

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human NKG2C.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: C-lectin type II protein; CD159 antigen-like family member A; CD159 antigen-like family member C; CD159a; CD159c; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NK cell receptor C; NK cell receptor E; NK cell receptor F; NKG2-1/B activating NK receptor; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NKG2-E type II integral membrane protein; NKG2-E-activating NK receptor; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor

          View more View less

          Gene Aliases: CD159A; CD159c; KLRC1; KLRC2; KLRC3; KLRC4; NKG2; NKG2-C; NKG2-E; NKG2-F; NKG2A; NKG2C; NKG2E; NKG2F

          View more View less

          UniProt ID: (Human) P26715, (Human) P26717, (Human) Q07444, (Human) O43908

          View more View less

          Entrez Gene ID: (Human) 3821, (Human) 3822, (Human) 3823, (Human) 8302

          View more View less

          Function(s)
          transmembrane signaling receptor activity protein binding MHC class I protein complex binding carbohydrate binding protein antigen binding
          Process(es)
          cellular defense response natural killer cell mediated immunity signal transduction innate immune response cell surface receptor signaling pathway regulation of immune response
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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