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PA1-4174 detects NKIAMRE in human samples.
PA1-4174 has been successfully used in Western blot procedures.
The PA1-4174 immunogen is a synthetic peptide corresponding to residues N(414) C N G L K E N P H C G G S V(428) of the 50 kDa human NKIAMRE.
Maintain at 4ºC for 3 months or at -20ºC for longer periods. Stable for 1 year. Avoid freeze/thaw cycles.
The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cyclin-dependent kinase-like 3; serine-threonine protein kinase NKIAMRE; Serine/threonine-protein kinase NKIAMRE
Gene Aliases: CDKL3; NKIAMRE
UniProt ID: (Human) Q8IVW4
Entrez Gene ID: (Human) 51265
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