Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
NKX6-2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
NKX6-2 Antibody (PA5-48988) in WB
Western blot analysis of NKX6-2 in K562 whole cell lysate. Samples were incubated with NKX6-2 polyclonal antibody (Product # PA5-48988) using a dilution of 1:1,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Predicted band size: 29 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-48988
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human NKX6-2.
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2634444
Target Information
Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: glial and testis-specific homeobox protein; homeobox 6B; Homeobox protein NK-6 homolog B; Homeobox protein Nkx-6.2; NK homeobox family 6, B; NK6 transcription factor related, locus 2
Gene Aliases: GTX; NKX6-2; NKX6.2; NKX6B
UniProt ID: (Human) Q9C056
Entrez Gene ID: (Human) 84504
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
negative regulation of cell fate commitment
positive regulation of cell fate commitment
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
central nervous system myelination
endocrine pancreas development
negative regulation of glial cell differentiation
positive regulation of glial cell differentiation
neuromuscular process controlling balance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support