Proteintech

NLGN1 Monoclonal Antibody (2D1A12)

1 Reference
View all (25) Neuroligin 1 antibodies

Promotion

View available promotion(s)

Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

66964-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:10,000
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:800
-
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rabbit, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2D1A12

Immunogen

NLGN1 Fusion Protein Ag6356

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1000 µg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: MGC45115; neuroligin 1; Neuroligin I; Neuroligin-1; NLG 1

View more View less

Gene Aliases: 6330415N05Rik; BB179718; KIAA1070; mKIAA1070; NL1; Nlg1; NLGN1

View more View less

UniProt ID: (Human) Q8N2Q7, (Mouse) Q99K10, (Rat) Q62765

View more View less

Entrez Gene ID: (Human) 22871, (Rabbit) 100357080, (Mouse) 192167, (Rat) 116647

View more View less

Function(s)
receptor activity PDZ domain binding neurexin family protein binding protein dimerization activity cell adhesion molecule binding carboxylic ester hydrolase activity scaffold protein binding protein binding
Process(es)
regulation of respiratory gaseous exchange by neurological system process protein targeting cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules neuron cell-cell adhesion nervous system development synapse assembly positive regulation of circadian sleep/wake cycle, wakefulness synaptic vesicle targeting calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules neuron projection development positive regulation of synaptic transmission, GABAergic protein localization to synapse establishment of protein localization regulation of neuron differentiation synaptic vesicle transport rhythmic process cytoskeletal matrix organization at active zone modulation of synaptic transmission synapse organization protein homooligomerization protein heterotetramerization positive regulation of filopodium assembly positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic inhibitory postsynaptic potential long-term synaptic potentiation positive regulation of dendritic spine development negative regulation of dendritic spine morphogenesis terminal button organization synaptic vesicle clustering postsynaptic membrane assembly presynaptic membrane assembly AMPA glutamate receptor clustering NMDA glutamate receptor clustering neurexin clustering involved in presynaptic membrane assembly postsynaptic density protein 95 clustering receptor localization to synapse positive regulation of ruffle assembly positive regulation of synaptic vesicle endocytosis positive regulation of protein localization to synapse positive regulation of intracellular signal transduction positive regulation of synaptic vesicle exocytosis regulation of N-methyl-D-aspartate selective glutamate receptor activity regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity positive regulation of excitatory postsynaptic potential positive regulation of synaptic vesicle clustering neuronal signal transduction metabolic process neuronal ion channel clustering
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support