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Invitrogen
NLGN4X (Neuroligin-4) Monoclonal Antibody (CSTEM30), PE, eBioscience™
FIGURE: 1 / 1
NLGN4X (Neuroligin-4) Antibody (12-9158-42) in Flow
Staining of a mixture of normal human iPSC and the murine C2C12 cell line with Anti-Human TRA-1-60 (Podocalyxin) PerCP-eFluor® 710 (Product # 46-8863-82) and Mouse IgG2a kappa Isotype Control, PE (Product # 12-4724-82) (left) or Anti-Human NLGN4X (Neuroligin-4) PE (right). Viable cells, as determined by Fixable Viability Dye eFluor® 450 (Product # 65-0863-14), were used for analysis.
Product Details
12-9158-42
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Recommended Isotype Control
Class
Monoclonal
Type
Antibody
Clone
CSTEM30
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
5 µL/Test
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2716932
Product Specific Information
This monoclonal antibody CSTEM30 reacts with human Neuroligin-4, X linked, also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X.
Applications Reported: This CSTEM30 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This CSTEM30 antibody has been pre-diluted and tested by flow cytometric analysis of human iPSCs. This may be used at 5 µL (0.06 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
Target Information
Neuroligin-4, X linked (also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge together the synaptic cleft and have an essential role in synaptic transmissions between neurons. There are 5 neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y. Mutations in NLGN3 and NLGN4X are linked to Autism Spectrum Disorders (ASD). The expression of neuroligin-4, X-linked has been reported on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HNLX; MGC22376; Neuroligin X; Neuroligin-4, X-linked; NLGN
Gene Aliases: ASPGX2; AUTSX2; HLNX; HNL4X; KIAA1260; NLGN4; NLGN4X; UNQ365/PRO701
UniProt ID: (Human) Q8N0W4
Entrez Gene ID: (Human) 57502
brainstem development
neuron cell-cell adhesion
learning
cerebellum development
neuron differentiation
adult behavior
social behavior
organ growth
cell-cell junction organization
synapse organization
vocalization behavior
negative regulation of excitatory postsynaptic potential
presynaptic membrane assembly
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