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Abnova
NLRP11 Polyclonal Antibody, MaxPab™
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Product Details
H00204801-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NLRP11 (NP_659444.1, 1 a.a. approximately 1033 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAESDSTDFD LLWYLENLSD KEFQSFKKYL ARKILDFKLP QFPLIQMTKE ELANVLPISY EGQYIWNMLF SIFSMMRKED LCRKIIGRRN RNQEACKAVM RRKFMLQWES HTFGKFHYKF FRDVSSDVFY ILQLAYDSTS YYSANNLNVF LMGERASGKT IVINLAVLRW IKGEMWQNMI SYVVHLTSHE INQMTNSSLA ELIAKDWPDG QAPIADILSD PKKLLFILED LDNIRFELNV NESALCSNST QKVPIPVLLV SLLKRKMAPG CWFLISSRPT RGNNVKTFLK EVDCCTTLQL SNGKREIYFN SFFKDRQRAS AALQLVHEDE ILVGLCRVAI LCWITCTVLK RQMDKGRDFQ LCCQTPTDLH AHFLADALTS EAGLTANQYH LGLLKRLCLL AAGGLFLSTL NFSGEDLRCV GFTEADVSVL QAANILLPSN THKDRYKFIH LNVQEFCTAI AFLMAVPNYL IPSGSREYKE KREQYSDFNQ VFTFIFGLLN ANRRKILETS FGYQLPMVDS FKWYSVGYMK HLDRDPEKLT HHMPLFYCLY ENREEEFVKT IVDALMEVTV YLQSDKDMMV SLYCLDYCCH LRTLKLSVQR IFQNKEPLIR PTASQMKSLV YWREICSLFY TMESLRELHI FDNDLNGISE RILSKALEHS SCKLRTLKLS YVSTASGFED LLKALARNRS LTYLSINCTS ISLNMFSLLH DILHEPTCQI SHLSLMKCDL RASECEEIAS LLISGGSLRK LTLSSNPLRS DGMNILCDAL LHPNCTLISL VLVFCCLTEN CCSALGRVLL FSPTLRQLDL CVNRLKNYGV LHVTFPLLFP TCQLEELHLS GCFFSSDICQ YIAIVIATNE KLRSLEIGSN KIEDAGMQLL CGGLRHPNCM LVNIGLEECM LTSACCRSLA SVLTTNKTLE RLNLLQNHLG NDGVAKLLES LISPDCVLKV VGLPLTGLNT QTQQLLMTVK ERKPSLIFLS ETWSLKEGRE IGVTPASQPG SIIPNSNLDY MFFKFPRMSA AMRTSNTASR QPL
Target Information
NALP11 is a 1033 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, six LRR (leucine-rich) repeats and a NACHT domain. Reports suggest that it is a short NALP involved in inflammation potential. NALP proteins are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes. The DAPIN domain is necessary and sufficient for suppression of NF-kappa B activation induced by TNF and for inducing IL-1B secretion in collaboration with Caspase-1. It is involved in interaction with PYCARD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NACHT, leucine rich repeat and PYD containing 11; NACHT, LRR and PYD domains-containing protein 11; NLR family, pyrin domain containing 11; Nucleotide-binding oligomerization domain protein 17; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11; PAAD- and NACHT-containing protein 10B; PAAD-and NACHT domain-containing protein 10; PYRIN-containing APAF1-like protein 6
Gene Aliases: CLR19.6; NALP11; NLRP11; NOD17; PAN10; PYPAF6; PYPAF7
UniProt ID: (Human) P59045
Entrez Gene ID: (Human) 204801
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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