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Product Details
PA5-119311
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein Non Metastatic Cells 3, Protein NM23A. The antigen corresponds to amino acid range 1-168 of the target protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2903809
Target Information
NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DR-nm23; expressed in non-metastatic cells 3; NDK 3; NDP kinase 3; NDP kinase C; NDPKC; nm23-H3; nm23-M3; non-metastatic cells 3, protein expressed in; Nucleoside diphosphate kinase 3; Nucleoside diphosphate kinase C; nucleoside diphosphate kinase DR-nm23
Gene Aliases: 1810009F08Rik; AI413736; c371H6.2; DR-nm23; Ndk3; NDPK-C; NDPKC; Nm23-DR; NM23-H3; Nm23-M3; NM23H3; NME3
UniProt ID: (Human) Q13232, (Mouse) Q9WV85
Entrez Gene ID: (Pig) 100514398, (Human) 4832, (Mouse) 79059
purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
nucleotide metabolic process
nucleoside triphosphate biosynthetic process
phosphorylation
regulation of apoptotic process
apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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