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Invitrogen
NME5 Polyclonal Antibody
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FIGURE: 1 / 5
NME5 Antibody (PA5-145309) in IHC (P)
Immunohistochemistry (Paraffin) analysis of NME5 in Human Kidney Tissue. Samples were incubated in NME5 polyclonal antibody (Product # PA5-145309) using a dilution of 20 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG at a dilution of 2 µg/mL and DAB staining.
Product Details
PA5-145309
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human NME5 protein, Ile3-Lys194 (Accession #P56597)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3093539
Target Information
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exonuclease NME5; expressed in non-metastatic cells 5; Inhibitor of p53-induced apoptosis-beta; IPIA-beta; NDK-H 5; NDP kinase homolog 5; nm23-H5; nm23-M5; NME/NM23 family member 5; non-metastatic cells 5 protein expressed in; non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nucleoside diphosphate kinase homolog 5; radial spoke 23 homolog; Rsph23; Testis-specific nm23 homolog
Gene Aliases: 1700019D05Rik; NM23-H5; Nm23-M5; NM23H5; NME5; RSPH23
UniProt ID: (Human) P56597, (Mouse) Q99MH5
Entrez Gene ID: (Human) 8382, (Mouse) 75533, (Rat) 688903
epithelial cilium movement
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
spermatogenesis
spermatid development
nucleoside metabolic process
ventricular system development
cilium assembly
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
response to reactive oxygen species
multicellular organism development
cell differentiation
spermatid differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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