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Invitrogen
NME7 Polyclonal Antibody
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NME7 Antibody (PA5-78647) in WB
Western blot analysis of NME7 in various lysates. Samples were incubated with NME7 polyclonal antibody (Product # PA5-78647) using a dilution of 1:3,000. A. 20 µg human embryonic stem cell whole cell lysate/extract; B. 20 µg whole cell lysate/extract of human LUC shRNA-transfected human embryonic stem cells; C. 20 µg whole cell lysate/extract of human Nme7-1 shRNA-transfected human embryonic stem cells. Separated by 10 % SDS-PAGE.
Product Details
PA5-78647
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse nm23-H7.
Conjugate
Form
Liquid
Concentration
1.08 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2736233
Product Specific Information
Positive Control: human embryonic stem cell, human LUC shRNA-transfected human embryonic stem cells, human Nme7-1 shRNA-transfected human embryonic stem cells
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exonuclease NME7; cilia and flagella associated protein 67; NDK 7; NDP kinase 7; nm23-H7; non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase); nucleoside diphosphate kinase 7; Nucleoside diphosphate kinase homolog 7; nucleoside-diphosphate kinase; nucleoside-diphosphate kinase 7; Protein kinase NME7
Gene Aliases: CFAP67; D530024H21Rik; MN23H7; NDK 7; NDK7; nm23-H7; Nm23-M7; Nm23-r7; NME7
UniProt ID: (Human) Q9Y5B8, (Mouse) Q9QXL8
Entrez Gene ID: (Human) 29922, (Mouse) 171567
epithelial cilium movement
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
determination of left/right symmetry
brain development
nucleotide metabolic process
phosphorylation
intraciliary transport
ciliary receptor clustering involved in smoothened signaling pathway
left/right pattern formation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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