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Product Details
H00023057-M04
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
2G8
Immunogen
NMNAT2 (AAH20998, 1 a.a. approximately 302 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MEIQELEEIQ ACQGLWEVFV TLSERARDYL HKTGRFIVIG GIVSPVHDSY GKQGLVSSRH RLIMCQLAVQ NSDWIRVDPW ECYQDTWQTT CSVLEHHRDL MKRVTGCILS NVNTPSMTPV IGQPQNETPQ PIYQNSNVAT KPTAAKILGK VGESLSRICC VRPPVERFTF VDENANLGTV MRYEEIELRI LLLCGSDLLE SFCIPGLWNE ADMEVIVGDF GIVVVPRDAA DTDRIMNHSS ILRKYKNNIM VVKDDINHPM SVVSSTKSRL ALQHGDGHVV DYLSQPVIDY ILKSQLYINA SG
Target Information
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NaMN adenylyltransferase 2; Nicotinamide mononucleotide adenylyltransferase 2; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinate-nucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NMN/NaMN adenylyltransferase 2; pyridine nucleotide adenylyltransferase 2
Gene Aliases: C1orf15; KIAA0479; NMNAT2; PNAT2
UniProt ID: (Human) Q9BZQ4
Entrez Gene ID: (Human) 23057
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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