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Proteintech
NMNAT3 Polyclonal Antibody
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Product Details
13236-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NMNAT3 Fusion Protein Ag3965 (38-252 aa encoded by BC034374)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MYQVIQGII SPVNDTYGKK DLAASHHRVA MARLALQTSD WIRVDPWESE QAQWMETVKV LRHHHSKLLR SPPQMEGPDH GKALFSTPAA VPELKLLCGA DVLKTFQTPN LWKDAHIQEI VEKFGLVCVG RVGHDPKGYI AESPILRMHQ HNIHLAKEPV QNEISATYIR RALGQGQSVK YLIPDAVITY IKDHGLYTKG STWKGKSTQS TEGKTS (38-252 aa encoded by BC034374)
Target Information
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: naMN adenylyltransferase 1; NaMN adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; Nicotinamide-nucleotide adenylyltransferase 3; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3; nicotinate-nucleotide adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; NMN/NaMN adenylyltransferase 3; PNAT-3; Pyridine nucleotide adenylyltransferase 3
Gene Aliases: 4933408N02Rik; FKSG76; NMNAT3; PNAT-3; PNAT3
UniProt ID: (Human) Q96T66, (Mouse) Q99JR6
Entrez Gene ID: (Human) 349565, (Mouse) 74080, (Rat) 363118
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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