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NOC3L Antibody (PA5-36501) in WB
Western blot analysis of NOC3L in Lane 1: HCT116 whole cell lysate (20 µg), Lane 2: HepG2 whole cell lysate (20 µg), Lane 3: AML-12 whole cell lysate (20 µg), Lane 4: H9C2 whole cell lysate (40 µg). Samples were incubated with NOC3L polyclonal antibody (Product # PA5-36501) at a dilution of 1:1,000.
Product Details
PA5-36501
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 417-436 of human NOC3L
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2553556
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 93 kDa.
Purity is >95% by SDS-PAGE.
Target Information
GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from "classical" C/EBP binding sites, recognizing instead unique "nonclassical" sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC3L, also designated factor for adipocyte differentiation 24 or Fad24, promotes adipogenesis by controlling DNA replication during the early stages of mitotic clonal expansion (MCE).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Factor for adipocyte differentiation 24; NOC3 protein homolog; NOC3-like DNA replication regulator; NOC3-like protein; NOC3L DNA replication regulator; nucleolar complex associated 3 homolog; Nucleolar complex protein 3 homolog; Nucleolar complex-associated protein 3-like protein
Gene Aliases: AD24; AF233884; C10orf117; FAD24; NOC3L; RGD1560656
UniProt ID: (Human) Q8WTT2, (Mouse) Q8VI84
Entrez Gene ID: (Human) 64318, (Mouse) 57753, (Rat) 361753
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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