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Product Details
16361-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NOL6 Fusion Protein Ag8368 (294-644 aa encoded by BC008852)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RVAYQREPQ ILKEVQSPEG MISLRDTAAS LRLERDTRQL PLLTSALHGL QQQHPAFSGV ARLAKRWVRA QLLGEGFADE SLDLVAAALF LHPEPFTPPS SPQVGFLRFL FLVSTFDWKN NPLFVNLNNE LTVEEQVEIR SGFLAARAQL PVMVIVTPQD RKNSVWTQDG PSAQILQQLV VLAAEALPML EKQLMDPRGP GDIRTVFRPP LDIYDVLIRL SPRHIPRHRQ AVDSPAASFC RGLLSQPGPS SLMPVLGYDP PQLYLTQLRE AFGDLALFFY DQHGGEVIGV LWKPTSFQPQ PFKASSTKGR MVMSRGGELV MVPNVEAILE DFAVLGEGLV QTVEARSERW TV (294-644 aa encoded by BC008852)
Target Information
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Nrap; Nucleolar protein 6; nucleolar protein 6 (RNA-associated); nucleolar protein family 6 (RNA-associated); Nucleolar RNA-associated protein
Gene Aliases: AA410091; bA311H10.1; NOL6; NRAP; UTP22
UniProt ID: (Human) Q9H6R4, (Mouse) Q6PAN8
Entrez Gene ID: (Human) 65083, (Mouse) 230082, (Rat) 313167
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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