Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVIVTPQDRK NSVWTQDGPS AQILQQLVVL AAEALPMLEK QLMDPRGPGD IRTVFRPPLD IYDVLIRLSP RHIPRHRQAV DSPAASFCRG LLSQPGPSSL MPVLGYDPPQ LYLTQLREAF GDLALFFYDQ HGGEVIGVLW KPTSFQPQPF KASSTKGRMV MSRGGELVMV PNVEAILEDF AVLGEGLVQT VEARSERWTV
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Nrap; Nucleolar protein 6; nucleolar protein 6 (RNA-associated); nucleolar protein family 6 (RNA-associated); Nucleolar RNA-associated protein
Gene Aliases: bA311H10.1; NOL6; NRAP; UTP22
UniProt ID: (Human) Q9H6R4
Entrez Gene ID: (Human) 65083
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