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Proteintech
NONO Polyclonal Antibody, CoraLite® Plus 647
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Product Details
CL647-11058
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
654/674 nm
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: IAKVELDNMP LRGKQLRVRF ACHSASLTVR NLPQYVSNEL LEEAFSVFGQ VERAVVIVDD RGRPSGKGIV EFSGKPAARK ALDRCSEGSF LLTTFPRPVT VEPMDQLDDE EGLPEKLVIK NQQFHKEREQ PPRFAQPGSF EYEYAMRWKA LIEMEKQQQD QVDRNIKEAR EKLEMEMEAA RHEHQVMLMR QDLMRRQEEL RRMEELHNQE VQKRKQLELR QEEERRRREE EMRRQQEEMM RRQQEGFKGT FPDAREQEIR MGQMAMGGAM GINNRGAMPP APVPAGTPAP PGPATMMPDG TLGLTPPTTE RFGQAATMEG IGAIGGTPPA FNRAAPGAEF APNKRRRY
Target Information
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; DNA-binding p52/p100 complex, 52 kDa subunit; HGNC:7871; NMT-1; NMT55; non-POU domain-containing octamer (ATGCAAAT) binding protein; Non-POU domain-containing octamer-binding protein; non-POU-domain-containing; non-POU-domain-containing, octamer-binding protein; NonO protein; p54(nrb); protein phosphatase 1, regulatory subunit 114
Gene Aliases: AA407051; AV149256; MRXS34; NMT55; nonA; NONO; NRB54; P54; P54NRB; PPP1R114
UniProt ID: (Human) Q15233, (Mouse) Q99K48, (Rat) Q5FVM4
Entrez Gene ID: (Human) 4841, (Mouse) 53610, (Rat) 317259
DNA repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
cellular response to DNA damage stimulus
circadian rhythm
RNA splicing
regulation of circadian rhythm
negative regulation of transcription, DNA-templated
rhythmic process
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
mRNA splicing, via spliceosome
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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