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Proteintech
NONO Monoclonal Antibody (2A2B10)
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Product Details
66361-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2A2B10
Immunogen
NONO Fusion Protein Ag17609 (124-471 aa encoded by BC010049)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IAKVELDNM PLRGKQLRVR FACHSASLTV RNLPQYVSNE LLEEAFSVFG QVERAVVIVD DRGRPSGKGI VEFSGKPAAR KALDRCSEGS FLLTTFPRPV TVEPMDQLDD EEGLPEKLVI KNQQFHKERE QPPRFAQPGS FEYEYAMRWK ALIEMEKQQQ DQVDRNIKEA REKLEMEMEA ARHEHQVMLM RQDLMRRQEE LRRMEELHNQ EVQKRKQLEL RQEEERRRRE EEMRRQQEEM MRRQQEGFKG TFPDAREQEI RMGQMAMGGA MGINNRGAMP PAPVPAGTPA PPGPATMMPD GTLGLTPPTT ERFGQAATME GIGAIGGTPP AFNRAAPGAE FAPNKRRRY (124-471 aa encoded by BC010049)
Target Information
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; DNA-binding p52/p100 complex, 52 kDa subunit; HGNC:7871; NMT-1; NMT55; non-POU domain-containing octamer (ATGCAAAT) binding protein; Non-POU domain-containing octamer-binding protein; non-POU-domain-containing; non-POU-domain-containing, octamer-binding protein; NonO protein; p54(nrb); protein phosphatase 1, regulatory subunit 114
Gene Aliases: AA407051; AV149256; MRXS34; NMT55; nonA; NONO; NRB54; P54; P54NRB; PPP1R114
UniProt ID: (Human) Q15233, (Mouse) Q99K48, (Rat) Q5FVM4
Entrez Gene ID: (Human) 4841, (Mouse) 53610, (Rat) 317259
DNA repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
cellular response to DNA damage stimulus
circadian rhythm
RNA splicing
regulation of circadian rhythm
negative regulation of transcription, DNA-templated
rhythmic process
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
mRNA splicing, via spliceosome
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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