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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • NOX2 Antibodies

          Proteintech

          NOX2 Polyclonal Antibody

          139 References
          View all (19) NOX2 antibodies
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite NOX2 Polyclonal Antibody

          • Antibody Testing Data (11)
          NOX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          NOX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 11

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          NOX2 Antibody (19013-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded Human tonsillitis tissue slide using (Product # 19013-1-AP) NOX2 antibody at dilution of 1:1,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NOX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NOX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NOX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NOX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NOX2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          NOX2 Antibody in Western Blot (WB)
          NOX2 Antibody in Western Blot (WB)
          NOX2 Antibody in Western Blot (WB)
          NOX2 Antibody in Western Blot (WB)
          NOX2 Antibody in Western Blot (WB)
          NOX2 Antibody in Western Blot (WB)

          Product Details

          19013-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 111 publications 111 publications

          Immunohistochemistry (IHC)

          -
          View 12 publications 12 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:400
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:1,000
          -

          Immunocytochemistry (ICC/IF)

          -
          View 10 publications 10 publications

          Miscellaneous PubMed (MISC)

          -
          View 2 publications 2 publications

          Not applicable (N/A)

          -
          View 4 publications 4 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          NOX2 Fusion Protein Ag5536 (422-577 aa encoded by BC032720)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: SILKSVWYK YCNNATNLKL KKIYFYWLCR DTHAFEWFAD LLQLLESQMQ ERNNAGFLSY NIYLTGWDES QANHFAVHHD EEKDVITGLK QKTLYGRPNW DNEFKTIASQ HPNTRIGVFL CGPEALAETL SKQSISNSES GPRGVHFIFN KENF (422-577 aa encoded by B C032720)

          Target Information

          Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase complex expresses in phagocytes, neuroepithelial bodies, vascular smooth muscle cells, and endothelial cells. It includes a membrane bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. The p22- and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. Mox1 and gp91 contain identical C-terminal sequence identity, yet possess distinct expression patterns. gp91-phox expresses in eosinophils, neutrophils, monocytes, and B-lymphocytes, whereas Mox1 is predominantly detected in the colon, with low expression in the uterus and prostate.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CGD91-phox; Cytochrome b(558) subunit beta; cytochrome b-245 beta polypeptide; Cytochrome b-245 heavy chain; cytochrome b-245, beta polypeptide; Cytochrome b558 subunit beta; endothelial type gp91-phox; GP91 PHOX; gp91-1; gp91-phox; GP911; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; p22 phagocyte B-cytochrome; p91PHOX; Superoxide-generating NADPH oxidase heavy chain subunit

          View more View less

          Gene Aliases: AMCBX2; C88302; CGD; CGD91-phox; CYBB; Cyd; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX

          View more View less

          UniProt ID: (Human) P04839, (Mouse) Q61093

          View more View less

          Entrez Gene ID: (Human) 1536, (Rat) 66021, (Mouse) 13058

          View more View less

          Function(s)
          voltage-gated ion channel activity protein binding electron carrier activity superoxide-generating NADPH oxidase activity heme binding metal ion binding protein heterodimerization activity flavin adenine dinucleotide binding NAD(P)H oxidase activity N-ethylmaleimide reductase activity oxidoreductase activity reduced coenzyme F420 dehydrogenase activity sulfur oxygenase reductase activity malolactic enzyme activity NADPH:sulfur oxidoreductase activity epoxyqueuosine reductase activity
          Process(es)
          superoxide metabolic process inflammatory response response to nutrient response to drug superoxide anion generation innate immune response respiratory burst hydrogen peroxide biosynthetic process oxidation-reduction process transport ion transport regulation of ion transmembrane transport response to reactive oxygen species antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent cell redox homeostasis vascular endothelial growth factor receptor signaling pathway
          It has to be done as per old AB suggested Products section.
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