Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Abnova
NPHP4 Monoclonal Antibody (4D4)
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
H00261734-M01A
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM, kappa
Class
Monoclonal
Type
Antibody
Clone
4D4
Immunogen
NPHP4 (NP_055917.1, 1317 a.a. approximately 1426 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: ASWLVCLCCR QPLISKAFEI MLAAGEGKGV NKRITYTNPY PSRRTFHLHS DHPELLRFRE DSFQVGGGET YTIGLQFAPS QRVGEEEILI YINDHEDKNE EAFCVKVIYQ
Target Information
This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Nephrocystin-4; Nephroretinin; POC10 centriolar protein homolog
Gene Aliases: KIAA0673; NPHP4; POC10; SLSN4
UniProt ID: (Human) O75161
Entrez Gene ID: (Human) 261734
signal transduction
visual behavior
single organismal cell-cell adhesion
actin cytoskeleton organization
sperm motility
hippo signaling
photoreceptor cell outer segment organization
photoreceptor cell maintenance
retina development in camera-type eye
negative regulation of canonical Wnt signaling pathway
positive regulation of bicellular tight junction assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support