Product References
A ribosomal gene panel predicting a novel synthetic lethality in non-BRCAness tumors.
Signal transduction and targeted therapy
Zhang C,Guo Q,Chen L,Wu Z,Yan XJ,Zou C,Zhang Q,Tan J,Fang T,Rao Q,Li Y,Shen S,Deng M,Wang L,Gao H,Yu J,Li H,Zhang C,Nowsheen S,Kloeber J,Zhao F,Yin P,Teng C,Lin Z,Song K,Yao S,Yao L,Wu L,Zhang Y,Cheng X,Gao Q,Yuan J,Lou Z,Zhang JS
32-5200 was used in Immunocytochemistry to identify a marker gene panel for HR-proficient patients and reveals a broader application of PARP inhibitor/cisplatin in cancer therapy.
Wed May 10 00:00:00 UTC 2023
Expansion microscopy of neutrophil nuclear structure and extracellular traps.
Biophysical reports
Holsapple JS,Schnitzler L,Rusch L,Baldeweg TH,Neubert E,Kruss S,Erpenbeck L
32-5200 was used in Immunohistochemistry-immunofluorescence to show that expansion microscopy enables superresolved imaging of the highly dynamic structure of nuclei in immune cells.
Wed Mar 08 00:00:00 UTC 2023
Carcinogen-induced super-enhancer RNA promotes nasopharyngeal carcinoma metastasis through NPM1/c-Myc/NDRG1 axis.
American journal of cancer research
Jia Q,Deng H,Wu Y,He Y,Tang F
32-5200 was used in Western Blot to investigate the oncogenic mechanism of N,N'-Dinitrosopiperazine.
Wed Sep 13 00:00:00 UTC 2023
Super-multiplexing excitation spectral microscopy with multiple fluorescence bands.
Biomedical optics express
Chen K,Li W,Xu K
32-5200 was used in Immunocytochemistry-immunofluorescence to show an easy-to-implement, cost-effective microscopy system for visualizing complex cellular components with more colors and lower crosstalks.
Tue Nov 01 00:00:00 UTC 2022
Super-multiplexing excitation spectral microscopy with multiple fluorescence bands.
Biomedical optics express
Chen K,Li W,Xu K
32-5200 was used in Immunocytochemistry-immunofluorescence to show an easy-to-implement, cost-effective microscopy system for visualizing complex cellular components with more colors and lower crosstalks.
Tue Nov 01 00:00:00 UTC 2022
Doxorubicin induces prolonged DNA damage signal in cells overexpressing DEK isoform-2.
PloS one
Özçelik E,Kalaycı A,Çelik B,Avcı A,Akyol H,Kılıç İB,Güzel T,Çetin M,Öztürk MT,Çalışkaner ZO,Tombaz M,Yoleri D,Konu Ö,Kandilci A
32-5200 was used in Immunocytochemistry-immunofluorescence to study the role of DEK2 in cellular processes by overexpressing DEK2 in the HS-27A human bone marrow stromal cell line.
Wed Oct 05 00:00:00 UTC 2022
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
EMBO reports
Stadler D,Kächele M,Jones AN,Hess J,Urban C,Schneider J,Xia Y,Oswald A,Nebioglu F,Bester R,Lasitschka F,Ringelhan M,Ko C,Chou WM,Geerlof A,van de Klundert MA,Wettengel JM,Schirmacher P,Heikenwälder M,Schreiner S,Bartenschlager R,Pichlmair A,Sattler M,Unger K,Protzer U
32-5200 was used in Immunocytochemistry to highlight that ISGs may cooperate in their antiviral activity that may be explored for therapeutic targeting.
Fri Jun 04 00:00:00 UTC 2021
14-3-3γ prevents centrosome duplication by inhibiting NPM1 function.
Genes to cells : devoted to molecular & cellular mechanisms
Bose A,Modi K,Dey S,Dalvi S,Nadkarni P,Sudarshan M,Kundu TK,Venkatraman P,Dalal SN
32-5200 was used in Western Blot to identify a novel role of 14-3-3γ in regulating centrosome licensing and a novel mechanism underlying the formation and dissociation of 14-3-3 ligand complexes dictated by conserved residues in the 14-3-3 family.
Tue Jun 01 00:00:00 UTC 2021
Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3.
Journal of experimental & clinical cancer research : CR
Jing Y,Jiang X,Lei L,Peng M,Ren J,Xiao Q,Tao Y,Tao Y,Huang J,Wang L,Tang Y,Yang Z,Yang Z,Zhang L
32-5200 was used in Western Blotting to indicate that HOTAIRM1 may be a promising therapeutic target for this distinct leukemia subtype.
Wed Oct 06 00:00:00 UTC 2021
Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.
eLife
Frottin F,Pérez-Berlanga M,Hartl FU,Hipp MS
32-5200 was used in Immunocytochemistry to analyze in a cellular model the relative toxicity of DPRs and RNA.
Wed Jun 23 00:00:00 UTC 2021
SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer.
Nature communications
Wang X,Zhang H,Sapio R,Yang J,Wong J,Zhang X,Guo JY,Pine S,Van Remmen H,Li H,White E,Liu C,Kiledjian M,Pestov DG,Steven Zheng XF
32-5200 was used in Immunohistochemistry to describe the generation of an inducible Sod1 knockout in KRAS-driven NSCLC mouse model.
Thu Apr 15 00:00:00 UTC 2021
Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing.
Light, science & applications
Chen K,Yan R,Xiang L,Xu K
32-5200 was used in Immunocytochemistry-immunofluorescence to investigate multiplexed fluorescenscence imaging with spectral microscopy.
Sat May 08 00:00:00 UTC 2021
Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing.
Light, science & applications
Chen K,Yan R,Xiang L,Xu K
32-5200 was used in Immunocytochemistry-immunofluorescence to investigate multiplexed fluorescenscence imaging with spectral microscopy.
Sat May 08 00:00:00 UTC 2021
Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing.
Light, science & applications
Chen K,Yan R,Xiang L,Xu K
32-5200 was used in Immunocytochemistry-immunofluorescence to investigate multiplexed fluorescenscence imaging with spectral microscopy.
Sat May 08 00:00:00 UTC 2021
Effects of Hydrogen Peroxide Stress on the Nucleolar Redox Environment and Pre-rRNA Maturation.
Frontiers in molecular biosciences
Sapio RT,Burns CJ,Pestov DG
32-5200 was used in Immunocytochemistry to introduce new tools for studies of the redox biology of the mammalian nucleolus and identifies pre-rRNA maturation steps sensitive to H2O2 stress.
Mon May 17 00:00:00 UTC 2021
On the prediction of neuronal microscale topology descriptors based on mesoscale recordings.
The European journal of neuroscience
Bonzanni M,Kaplan DL
32-5200 was used in ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, RNA Immunoprecipitation, Western Blot to explore the behaviour of in silico neuronal networks across different scales. We established ad hoc relations of several topological descriptors (average clustering coefficient, average path length, small-world propensity, modularity, network degree, synchronizability and fraction of long-term connections) between different scales upon application and empirical vali
Wed Sep 01 00:00:00 UTC 2021
Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer.
The Journal of experimental medicine
Bhattacharyya S,Oon C,Kothari A,Horton W,Link J,Sears RC,Sherman MH
32-5200 was used in Immunocytochemistry to demonstrate that MYC is coordinately regulated by cell-autonomous and microenvironmental signals, and establish CAF-derived FGF1 as a novel paracrine regulator of oncogenic transcription.
Mon Aug 03 00:00:00 UTC 2020
Accumulation of Nucleolar Inorganic Polyphosphate Is a Cellular Response to Cisplatin-Induced Apoptosis.
Frontiers in oncology
Xie L,Rajpurkar A,Quarles E,Taube N,Rai AS,Erba J,Sliwinski B,Markowitz M,Jakob U,Knoefler D
32-5200 was used in Immunohistochemistry-immunofluorescence to demonstrate that cancer cells respond to cisplatin treatment with the nucleolar accumulation of inorganic polyphosphate (polyP), a universally conserved high-energy compound.
Thu Jan 14 00:00:00 UTC 2021
Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence.
DNA repair
Burra S,Marasco D,Malfatti MC,Antoniali G,Virgilio A,Esposito V,Demple B,Galeone A,Tell G
32-5200 was used in Western Blotting to study the molecular details regulating Ape1 enzymatic activities on G4-telomeric sequences.
Tue Jan 01 00:00:00 UTC 2019
Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock.
eLife
Azkanaz M,Rodríguez López A,de Boer B,Huiting W,Angrand PO,Vellenga E,Kampinga HH,Bergink S,Martens JH,Schuringa JJ,van den Boom V
32-5200 was used in Immunocytochemistry-immunoflourescence to study the effects of heatshock on epigenetic regulators, revealing that the nucleolus acts as a quality control centre and enables recovery of the epigenome after heatshock.
Fri Jun 14 00:00:00 UTC 2019
The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair.
Scientific reports
Hensen F,Moretton A,van Esveld S,Farge G,Spelbrink JN
32-5200 was used in Western Blotting to show that EXD2 shows mitochondrial localisation, but is found predominantly associated with the mitochondrial outer-membrane.
Thu Mar 29 00:00:00 UTC 2018
XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
Nature
Hoch NC,Hanzlikova H,Rulten SL,Tétreault M,Komulainen E,Ju L,Hornyak P,Zeng Z,Gittens W,Rey SA,Staras K,Mancini GM,McKinnon PJ,Wang ZQ,Wagner JD,Yoon G,Caldecott KW
32-5200 was used in western blot to investigate the role of XRCC1 protein complexes in normal neurological function and identify PARP1 as a therapeutic target in DNA strand break repair-defective disease
Thu Jan 05 00:00:00 UTC 2017
Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.
Nucleic acids research
Hanzlikova H,Gittens W,Krejcikova K,Zeng Z,Caldecott KW
325200 was used in immunohistochemistry to investigate the roles of PARP2 and PARP3 during DNA break repair
Fri Mar 17 00:00:00 UTC 2017
Nuclear export factor 3 regulates localization of small nucleolar RNAs.
The Journal of biological chemistry
Li MW,Sletten AC,Lee J,Pyles KD,Matkovich SJ,Ory DS,Schaffer JE
32-5200 was used in Immunocytochemistry-immunoflourescence to identify nuclear export factor 3 as a transporter that alters the nucleocytoplasmic distribution of box C/D small nucleolar RNAs from the ribosomal protein L13a locus.
Fri Dec 08 00:00:00 UTC 2017
Multiplexed 3D super-resolution imaging of whole cells using spinning disk confocal microscopy and DNA-PAINT.
Nature communications
Schueder F,Lara-Gutiérrez J,Beliveau BJ,Saka SK,Sasaki HM,Woehrstein JB,Strauss MT,Grabmayr H,Yin P,Jungmann R
32-5200 was used in Immunocytochemistry to combine 3D DNA points accumulation for imaging in nanoscale topography with spinning disk confocal hardware to remove the requirement of complex hardware for single-molecule localisation microscopy in thick samples.
Tue Dec 12 00:00:00 UTC 2017
Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.
The Journal of clinical investigation
Naylor RM,Jeganathan KB,Cao X,van Deursen JM
32-5200 was used in Immunofluorescence to study the effect of overexpressing nuclear pore protein NUP88 on the probability of intestinal tumors in mice.
Mon Feb 01 00:00:00 UTC 2016
Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency.
Oncogene
Ceccon M,Merlo MEB,Mologni L,Poggio T,Varesio LM,Menotti M,Bombelli S,Rigolio R,Manazza AD,Di Giacomo F,Ambrogio C,Giudici G,Casati C,Mastini C,Compagno M,Turner SD,Gambacorti-Passerini C,Chiarle R,Voena C
32-5200 was used in western blot to study NPM-ALK-amplified cell lines resistant to ALK tyrosine kinase inhibitors
Thu Jul 21 00:00:00 UTC 2016
Expression of placenta-specific 8 in human oocytes, embryos, and models of in vitro implantation.
Fertility and sterility
Li M,Liu D,Wang L,Wang W,Wang A,Yao Y
32-5200 was used in immunocytochemistry to utilize human oocytes, models of in vitro implantation, and embryos to study expression of placenta-specific 8
Thu Sep 01 00:00:00 UTC 2016
Functional characterization and efficient detection of Nucleophosmin/NPM1 oligomers.
Biochemical and biophysical research communications
Lin J,Hisaoka M,Nagata K,Okuwaki M
325200 was used in western blot to examine the functional meaning of oligomerization of NPM1/nucleophosmin
Fri Nov 25 00:00:00 UTC 2016
Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.
Science (New York, N.Y.)
Woerner AC,Frottin F,Hornburg D,Feng LR,Meissner F,Patra M,Tatzelt J,Mann M,Winklhofer KF,Hartl FU,Hipp MS
32-5200 was used in Immunocytochemistry to analyze the compartment specificity of aggregate toxicity using artificial β-sheet proteins, as well as fragments of mutant huntingtin and TAR DNA binding protein-43 (TDP-43).
Fri Jan 08 00:00:00 UTC 2016
PPM1D controls nucleolar formation by up-regulating phosphorylation of nucleophosmin.
Scientific reports
Kozakai Y,Kamada R,Furuta J,Kiyota Y,Chuman Y,Sakaguchi K
325200 was used in immunocytochemistry and western blot to report that PPM1D modulates nucleolar formation by regulating NPM phosphorylation
Tue Sep 13 00:00:00 UTC 2016
Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells.
Blood
Martelli MP,Gionfriddo I,Mezzasoma F,Milano F,Pierangeli S,Mulas F,Pacini R,Tabarrini A,Pettirossi V,Rossi R,Vetro C,Brunetti L,Sportoletti P,Tiacci E,Di Raimondo F,Falini B
32-5200 was used in Immunocytochemistry to study the proteasome-dependent degradation of NPM1 leukaemic protein and apoptosis induced by all-trans retinoic acid plus arsenic trioxide in NPM1-mutated AML cell lines and primary patients' cells.
Thu May 28 00:00:00 UTC 2015
High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation.
Nucleic acids research
Sokka M,Rilla K,Miinalainen I,Pospiech H,Syväoja JE
32-5200 was used in immunocytochemistry to report that TopBP1 and ATR inhibit the synthesis of rRNA and activate the nucleolar stress pathway.
Tue May 26 00:00:00 UTC 2015
TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification.
Molecular and cellular biology
Neo SH,Itahana Y,Alagu J,Kitagawa M,Guo AK,Lee SH,Tang K,Itahana K
32-5200 was used in western blot to identify TRIM28/KAP1 as a novel ARF-binding protein and SUMO E3 ligase for NPM1/B23.
Sat Aug 01 00:00:00 UTC 2015
Pharmacologic inhibition of the CK2-mediated phosphorylation of B23/NPM in cancer cells selectively modulates genes related to protein synthesis, energetic metabolism, and ribosomal biogenesis.
Molecular and cellular biochemistry
Perera Y,Pedroso S,Borras-Hidalgo O,Vázquez DM,Miranda J,Villareal A,Falcón V,Cruz LD,Farinas HG,Perea SE
32-5200 was used in western blot to investigate the effect of CK2-mediated phosphorylation of B23/NPM on specific genes in cancer cells
Mon Jun 01 00:00:00 UTC 2015
An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding.
Biochemical and biophysical research communications
Fujiwara Y,Hase K,Wada K,Kabuta T
32-5200 was used in western blot to investigate the mechanism for the RNautophagy/DNautophagy effect of LAMP2C
Fri May 01 00:00:00 UTC 2015
Involvement of Nucleophosmin (NPM1/B23) in Assembly of Infectious HPV16 Capsids.
Papillomavirus research (Amsterdam, Netherlands)
Day PM,Thompson CD,Pang YY,Lowy DR,Schiller JT
32-5200 was used in Immunoprecipitation to demonstrate a role for the host nucleolar protein nucleophosmin (NPM1/B23) during assembly of HPV16 pseudovirus.
Tue Dec 01 00:00:00 UTC 2015
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.
Nature
Flach J,Bakker ST,Mohrin M,Conroy PC,Pietras EM,Reynaud D,Alvarez S,Diolaiti ME,Ugarte F,Forsberg EC,Le Beau MM,Stohr BA,Méndez J,Morrison CG,Passegué E
32-5200 was used in immunocytochemistry to study why HSC function declines with age
Thu Aug 14 00:00:00 UTC 2014
Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis.
Cell death and differentiation
de Poot SA,Lai KW,van der Wal L,Plasman K,Van Damme P,Porter AC,Gevaert K,Bovenschen N
32-5200 was used in western blot to study granzyme M-induced cell death.
Sat Mar 01 00:00:00 UTC 2014
KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo.
Cell cycle (Georgetown, Tex.)
Pekkonen P,Järviluoma A,Zinovkina N,Cvrljevic A,Prakash S,Westermarck J,Evan GI,Cesarman E,Verschuren EW,Ojala PM
32-5200 was used in western blot to test if a viral cyclin-CDK6 complex is a regulator of the Notch receptor
Thu Sep 10 00:00:00 UTC 2015
Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53.
Cell cycle (Georgetown, Tex.)
Reed SM,Hagen J,Tompkins VS,Thies K,Quelle FW,Quelle DE
32-5200 was used in Western Blotting to show that nuclear interactor of ARF and Mdm2 (NIAM) regulates 2 critical pathways controlling p53 function which are altered in human cancers, implying a potential role for NIAM in tumourigenesis.
Fri Aug 14 00:00:00 UTC 2015
Cellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein release.
Nucleus (Austin, Tex.)
Lindenboim L,Sasson T,Worman HJ,Borner C,Stein R
32-5200 was used in immunocytochemistry to assess induced Bax-regulated nuclear rupture and bubble budding followed by release of nuclear proteins due to cellular stress
Wed Sep 16 00:00:00 UTC 2015
Deregulated expression of Nucleophosmin 1 in gastric cancer and its clinicopathological implications.
BMC gastroenterology
Leal MF,Mazzotti TK,Calcagno DQ,Cirilo PD,Martinez MC,Demachki S,Assumpção PP,Chammas R,Burbano RR,Smith MC
32-5200 was used in western blot to examine NPM1 gene and protein expression in gastric tumors.
Fri Jan 10 00:00:00 UTC 2014
Nucleophosmin/B26 regulates PTEN through interaction with HAUSP in acute myeloid leukemia.
Leukemia
Noguera NI,Song MS,Divona M,Catalano G,Calvo KL,García F,Ottone T,Florenzano F,Faraoni I,Battistini L,Colombo E,Amadori S,Pandolfi PP,Lo-Coco F
32-5200 was used in western blot to elucidate the role of NPM-HAUSP in controlling PTEN deubiquitination and trafficking.
Mon Apr 01 00:00:00 UTC 2013
The role of 3D microenvironmental organization in MCF-7 epithelial-mesenchymal transition after 7 culture days.
Experimental cell research
Foroni L,Vasuri F,Valente S,Gualandi C,Focarete ML,Caprara G,Scandola M,D'Errico-Grigioni A,Pasquinelli G
32-5200 was used in immunohistochemistry (paraffin) to assess the extracellular matrix in tumor cells cultured in different 3D environments.
Mon Jun 10 00:00:00 UTC 2013
Identification of TSG101 functional domains and p21 loci required for TSG101-mediated p21 gene regulation.
PloS one
Lin YS,Chen YJ,Cohen SN,Cheng TH
32-5200 was used in western blot to study the mechanisms underlying the regulation of p21 gene expression by TSG101.
Mon Nov 24 00:00:00 UTC 2014
DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Cancer research
Fukawa T,Ono M,Matsuo T,Uehara H,Miki T,Nakamura Y,Kanayama HO,Katagiri T
32-5200 was used in western blot to identify and characterize the role of DDX31 in renal carcinogenesis.
Thu Nov 15 00:00:00 UTC 2012
Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug.
The American journal of pathology
Mercier I,Camacho J,Titchen K,Gonzales DM,Quann K,Bryant KG,Molchansky A,Milliman JN,Whitaker-Menezes D,Sotgia F,Jasmin JF,Schwarting R,Pestell RG,Blagosklonny MV,Lisanti MP
32-5200 was used in immunocytochemistry to assess the effects of host aging on mammary tumor growth.
Sun Jul 01 00:00:00 UTC 2012
Preparation and characterization of mesoporous bioactive glass/polycaprolactone nanofibrous matrix for bone tissues engineering.
Journal of materials science. Materials in medicine
Lin HM,Lin YH,Hsu FY
32-5200 was used in western blot to study the microstructural, physical, and biological properties of a polycaprolactone nanofibrous composite matrix.
Thu Nov 01 00:00:00 UTC 2012
Nucleolar proteins with altered expression in leukemic cell lines.
Leukemia research
Teittinen KJ,Kärkkäinen P,Salonen J,Rönnholm G,Korkeamäki H,Vihinen M,Kalkkinen N,Lohi O
32-5200 was used in immunocytochemistry to identify proteins whose expression is altered in the nucleoli of leukemic cells.
Wed Feb 01 00:00:00 UTC 2012
Nucleophosmin expression in renal cell carcinoma and oncocytoma.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Sari A,Calli A,Altinboga AA,Pehlivan FS,Gorgel SN,Balci U,Ermete M,Dincel C,Cakalagaoglu F
32-5200 was used in immunohistochemistry (paraffin) to determine the nucleophosmin/B23 expression in renal cell carcinomas and renal oncocytomas.
Thu Mar 01 00:00:00 UTC 2012
Sensitivity of tumor cells towards CIGB-300 anticancer peptide relies on its nucleolar localization.
Journal of peptide science : an official publication of the European Peptide Society
Perera Y,Costales HC,Diaz Y,Reyes O,Farina HG,Mendez L,Gómez RE,Acevedo BE,Gomez DE,Alonso DF,Perea SE
32-5200 was used in western blot to report that CIGB-300's antiproliferative activity on tumor cells strongly correlates with its nucleolar localization.
Sun Apr 01 00:00:00 UTC 2012
Analysis of spatial point patterns in nuclear biology.
PloS one
Weston DJ,Adams NM,Russell RA,Stephens DA,Freemont PS
32-5200 was used in immunocytochemistry to discuss methods used to examine the spatial arrangement of nuclear objects
Fri Sep 14 00:00:00 UTC 2012
The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells.
Oncogene
Donati G,Bertoni S,Brighenti E,Vici M,Treré D,Volarevic S,Montanaro L,Derenzini M
32-5200 was used in immunocytochemistry to investigate the effect of modulating the rRNA transcription rate on p53 induction in mammalian cells.
Thu Jul 21 00:00:00 UTC 2011
The role of RPGR in cilia formation and actin stability.
Human molecular genetics
Gakovic M,Shu X,Kasioulis I,Carpanini S,Moraga I,Wright AF
Thu Dec 15 00:00:00 UTC 2011
Remodeling of ribosomal genes in somatic cells by Xenopus egg extract.
Biochemical and biophysical research communications
Østrup O,Hyttel P,Klærke DA,Collas P
32-5200 was used in immunocytochemistry to report that an early reprogramming event remodels ribosomal chromatin and gene expression.
Fri Sep 02 00:00:00 UTC 2011
The enigmatic role of nucleophosmin in malignant melanoma: does it have an effect?
Indian journal of pathology & microbiology
Calli AO,Sari A,Evcim G,Altinboga A,Sadullahoglu C,Ermete M
32-5200 was used in immunohistochemistry (paraffin) to investigate prognostic markers of melanoma.
Thu Jan 19 00:00:00 UTC 2012
Intracellular serine protease inhibitor SERPINB4 inhibits granzyme M-induced cell death.
PloS one
de Koning PJ,Kummer JA,de Poot SA,Quadir R,Broekhuizen R,McGettrick AF,Higgins WJ,Devreese B,Worrall DM,Bovenschen N
32-5200 was used in western blot to investigate the interactions between SERPINB4 and human GrM.
Wed Feb 15 00:00:00 UTC 2012
Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction.
Molecular & cellular proteomics : MCP
Lewis AE,Sommer L,Arntzen MØ,Strahm Y,Morrice NA,Divecha N,D'Santos CS
32-5200 was used in western blot to investigate phosphoinositide-regulated nuclear functions
Tue Feb 01 00:00:00 UTC 2011
PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis.
Cell research
Zhu Z,Wang Y,Li X,Wang Y,Xu L,Wang X,Sun T,Dong X,Chen L,Mao H,Yu Y,Li J,Chen PA,Chen CD
32-5200 was used in immunocytochemistry to identify PHF8 as a demethylase of histone H3 lysine 9
Thu Jul 01 00:00:00 UTC 2010
Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.
Nucleic acids research
Fantini D,Vascotto C,Marasco D,D'Ambrosio C,Romanello M,Vitagliano L,Pedone C,Poletto M,Cesaratto L,Quadrifoglio F,Scaloni A,Radicella JP,Tell G
32-5200 was used in immunoprecipitation to report that five lysine residues in the APE1 N-terminal unstructured domain are important for the interaction of APE1 with both RNA and NPM1
Wed Dec 01 00:00:00 UTC 2010
ARF suppresses tumor angiogenesis through translational control of VEGFA mRNA.
Cancer research
Kawagishi H,Nakamura H,Maruyama M,Mizutani S,Sugimoto K,Takagi M,Sugimoto M
32-5200 was used in western blot to demonstrate that the nucleolar tumor suppressor p19(ARF) suppresses vascular endothelial growth factor A expression
Tue Jun 01 00:00:00 UTC 2010
Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis.
Science signaling
Wang Z,Udeshi ND,Slawson C,Compton PD,Sakabe K,Cheung WD,Shabanowitz J,Hunt DF,Hart GW
Tue Jan 12 00:00:00 UTC 2010
Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis.
Science signaling
Wang Z,Udeshi ND,Slawson C,Compton PD,Sakabe K,Cheung WD,Shabanowitz J,Hunt DF,Hart GW
Tue Jan 12 00:00:00 UTC 2010
Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis.
Science signaling
Wang Z,Udeshi ND,Slawson C,Compton PD,Sakabe K,Cheung WD,Shabanowitz J,Hunt DF,Hart GW
Tue Jan 12 00:00:00 UTC 2010
Ribosome-associated nucleophosmin 1: increased expression and shuttling activity distinguishes prognostic subtypes in chronic lymphocytic leukaemia.
British journal of haematology
Rees-Unwin KS,Faragher R,Unwin RD,Adams J,Brown PJ,Buckle AM,Pettitt A,Hutchinson CV,Johnson SM,Pulford K,Banham AH,Whetton AD,Lucas G,Mason DY,Burthem J
32-5200 was used in immunocytochemistry to describe the protein profiles of two distinct groups of chronic lymphocytic leukemia.
Mon Feb 01 00:00:00 UTC 2010
Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death.
BMC cancer
Piazza F,Manni S,Tubi LQ,Montini B,Pavan L,Colpo A,Gnoato M,Cabrelle A,Adami F,Zambello R,Trentin L,Gurrieri C,Semenzato G
Mon Oct 04 00:00:00 UTC 2010
Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death.
BMC cancer
Piazza F,Manni S,Tubi LQ,Montini B,Pavan L,Colpo A,Gnoato M,Cabrelle A,Adami F,Zambello R,Trentin L,Gurrieri C,Semenzato G
Mon Oct 04 00:00:00 UTC 2010
B23 interacts with PES1 and is involved in nucleolar localization of PES1.
Acta biochimica et biophysica Sinica
Zhang J,Yang Y,Wu J
Tue Dec 01 00:00:00 UTC 2009
TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation.
BMC biochemistry
Pitulescu ME,Teichmann M,Luo L,Kessel M
32-5200 was used in immunohistochemistry to review the transcription factors that the re-replication inhibitor Geminin binds
Wed Jun 10 00:00:00 UTC 2009
Mitochondrial p32 is a critical mediator of ARF-induced apoptosis.
Cancer cell
Itahana K,Zhang Y
32-5200 was used in western blot to examine the role of mitochondrial p32 in ARF-induced apoptosis
Sun Jun 01 00:00:00 UTC 2008
DNA damage-dependent translocation of B23 and p19 ARF is regulated by the Jun N-terminal kinase pathway.
Cancer research
Yogev O,Saadon K,Anzi S,Inoue K,Shaulian E
32-5200 was used in immunocytochemistry, immunoprecipitation, and western blot to study translocation of p14(ARF)/p19(ARF) and B23 into the nucleus
Sat Mar 01 00:00:00 UTC 2008
Binding to nucleophosmin determines the localization of human and chicken ARF but not its impact on p53.
Oncogene
Moulin S,Llanos S,Kim SH,Peters G
32-5200 was used in western blot to examine whether nucleolar localization determines the stability of ARF tumor suppressor gene
Thu Apr 10 00:00:00 UTC 2008
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes.
Nature
Frescas D,Guardavaccaro D,Bassermann F,Koyama-Nasu R,Pagano M
32-5200 was used in immunoprecipitation to characterize human JHDM1B.
Thu Nov 08 00:00:00 UTC 2007
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia.
Blood
Falini B,Martelli MP,Bolli N,Bonasso R,Ghia E,Pallotta MT,Diverio D,Nicoletti I,Pacini R,Tabarrini A,Galletti BV,Mannucci R,Roti G,Rosati R,Specchia G,Liso A,Tiacci E,Alcalay M,Luzi L,Volorio S,Bernard L,Guarini A,Amadori S,Mandelli F,Pane F,Lo-Coco F,Saglio G,Pelicci PG,Martelli MF,Mecucci C
32-5200 was used in immunohistochemistry to assess the role of nucleophosmin exon-12 mutations in adult acute myeloid leukemia
Fri Sep 15 00:00:00 UTC 2006
Hepatitis C virus core protein recruits nucleolar phosphoprotein B23 and coactivator p300 to relieve the repression effect of transcriptional factor YY1 on B23 gene expression.
Oncogene
Mai RT,Yeh TS,Kao CF,Sun SK,Huang HH,Wu Lee YH
Thu Jan 19 00:00:00 UTC 2006
Hepatitis C virus core protein recruits nucleolar phosphoprotein B23 and coactivator p300 to relieve the repression effect of transcriptional factor YY1 on B23 gene expression.
Oncogene
Mai RT,Yeh TS,Kao CF,Sun SK,Huang HH,Wu Lee YH
Thu Jan 19 00:00:00 UTC 2006
Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication.
Nature cell biology
Wang W,Budhu A,Forgues M,Wang XW
32-5200 was used in immunocytochemistry and western blot to propose that nucleophosmin is a Ran-Crm1 substrate that controls centrosome duplication
Mon Aug 01 00:00:00 UTC 2005
Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Cancer research
Dasgupta B,Yi Y,Chen DY,Weber JD,Gutmann DH
Fri Apr 01 00:00:00 UTC 2005
Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function.
Molecular and cellular biology
Korgaonkar C,Hagen J,Tompkins V,Frazier AA,Allamargot C,Quelle FW,Quelle DE
Tue Feb 01 00:00:00 UTC 2005
Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function.
Molecular and cellular biology
Korgaonkar C,Hagen J,Tompkins V,Frazier AA,Allamargot C,Quelle FW,Quelle DE
Tue Feb 01 00:00:00 UTC 2005
Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function.
Molecular and cellular biology
Korgaonkar C,Hagen J,Tompkins V,Frazier AA,Allamargot C,Quelle FW,Quelle DE
Tue Feb 01 00:00:00 UTC 2005
Proteomic characterization of oxidative dysfunction in human umbilical vein endothelial cells (HUVEC) induced by exposure to oxidized LDL.
Free radical research
Kinumi T,Ogawa Y,Kimata J,Saito Y,Yoshida Y,Niki E
32-5200 was used in western blot to investigate the effects of oxidized low-density lipoprotein treatment on endothelial cells
Thu Dec 01 00:00:00 UTC 2005
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis.
The Journal of biological chemistry
Li Y,Schwabe RF,DeVries-Seimon T,Yao PM,Gerbod-Giannone MC,Tall AR,Davis RJ,Flavell R,Brenner DA,Tabas I
Fri Jun 10 00:00:00 UTC 2005
Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways.
Molecular cancer research : MCR
Zhao L,Samuels T,Winckler S,Korgaonkar C,Tompkins V,Horne MC,Quelle DE
Wed Jan 01 00:00:00 UTC 2003
Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways.
Molecular cancer research : MCR
Zhao L,Samuels T,Winckler S,Korgaonkar C,Tompkins V,Horne MC,Quelle DE
Wed Jan 01 00:00:00 UTC 2003
