Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Alomone Labs, LTD
NPY2R Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 3
NPY2R Antibody (ANR-022-200UL) in ICC/IF
Expression of neuropeptide Y2receptor in rat dorsal root ganglion cells - Immunocytochemical staining of rat dorsal root ganglion (DRG) neurons. A, D. A paraformaldehyde-fixed and permeabilized DRG primary culture was stained with Anti-NPY2R Antibody (#ANR-022), (1:100) followed by Alexa-555-conjugated goat Anti-rabbit secondary Antibody . B, E. Nuclear fluorescence staining of cells using the membrane-permeable DNA dye Hoechst 33342. C. Merged images of panels A and B. F. Merged images of panels D and E. Magnification:A-C: x20E-F: x100.
Product Details
ANR-022-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CEQRLDAIHSEVSMTFKAK, corresponding to amino acid residues 346-364 of mouse NPY2R, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: MGC124241; MGC124242; MGC124244; Neuropeptide Y receptor type 2; neuropeptide Y receptor Y2-like; Neuropeptide y-y2; neuropeptide Y-Y2 receptor; neuropeptide Y/peptide YY-Y2 receptor; NPY-Y2 receptor; NPY2-R; Y2 receptor
Gene Aliases: NPY2-R; Npy2r
UniProt ID: (Mouse) P97295
Entrez Gene ID: (Mouse) 18167, (Rat) 66024
behavioral fear response
positive regulation of peptide secretion
outflow tract morphogenesis
cardiac left ventricle morphogenesis
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
nitric oxide mediated signal transduction
chemical synaptic transmission
positive regulation of cell-substrate adhesion
negative regulation of cAMP biosynthetic process
negative regulation of neurological system process
positive regulation of dopamine secretion
positive regulation of smooth muscle contraction
positive regulation of circadian sleep/wake cycle, non-REM sleep
secretion
negative regulation of synaptic transmission
negative regulation of secretion
regulation of sensory perception of pain
negative regulation of synaptic transmission, glutamatergic
negative regulation of excitatory postsynaptic potential
negative regulation of feeding behavior
positive regulation of cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support