Product References
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Journal of ethnopharmacology
Wu S,Tian C,Tu Z,Guo J,Xu F,Qin W,Chang H,Wang Z,Hu T,Sun X,Ning H,Li Y,Gou W,Hou W
Sat Jul 15 00:00:00 UTC 2023
Dehydroepiandrosterone protects against oleic acid-triggered mitochondrial dysfunction to relieve oxidative stress and inflammation via activation of the AMPK-Nrf2 axis by targeting GPR30 in hepatocytes.
Molecular immunology
Yao Y,Wang H,Yang Y,Jiang Z,Ma H
Wed Mar 01 00:00:00 UTC 2023
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
International immunopharmacology
Huang B,Hu G,Zong X,Yang S,He D,Gao X,Liu D
Wed Feb 01 00:00:00 UTC 2023
T Cell Nrf2/Keap1 Gene Editing Using CRISPR/Cas9 and Experimental Kidney Ischemia-Reperfusion Injury.
Antioxidants & redox signaling
Kurzhagen JT,Noel S,Lee K,Sadasivam M,Gharaie S,Ankireddy A,Lee SA,Newman-Rivera A,Gong J,Arend LJ,Hamad ARA,Reddy SP,Rabb H
Mon May 01 00:00:00 UTC 2023
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways.
The Journal of pharmacy and pharmacology
Zhang M,Zhang J,Zhu QM,Zhao WY,Lv X,Yi J,Huo XK,Wang MJ,Sun CP
Wed Feb 08 00:00:00 UTC 2023
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cellular signalling
Qiu D,Song S,Chen N,Bian Y,Yuan C,Zhang W,Duan H,Shi Y
Tue Aug 01 00:00:00 UTC 2023
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cellular signalling
Qiu D,Song S,Chen N,Bian Y,Yuan C,Zhang W,Duan H,Shi Y
Tue Aug 01 00:00:00 UTC 2023
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cellular signalling
Qiu D,Song S,Chen N,Bian Y,Yuan C,Zhang W,Duan H,Shi Y
Tue Aug 01 00:00:00 UTC 2023
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cellular signalling
Qiu D,Song S,Chen N,Bian Y,Yuan C,Zhang W,Duan H,Shi Y
Tue Aug 01 00:00:00 UTC 2023
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cellular signalling
Qiu D,Song S,Chen N,Bian Y,Yuan C,Zhang W,Duan H,Shi Y
Tue Aug 01 00:00:00 UTC 2023
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cellular signalling
Qiu D,Song S,Chen N,Bian Y,Yuan C,Zhang W,Duan H,Shi Y
Tue Aug 01 00:00:00 UTC 2023
Active Nrf2 signaling flexibly regulates HO-1 and NQO-1 in hypoxic Gansu Zokor (Eospalax cansus).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Li M,Peng Y,Chen W,Gao Y,Yang M,Li J,He J
Mon Jan 09 00:00:00 UTC 2023
Alpha-lipoic acid activates AMPK to protect against oxidative stress and apoptosis in rats with diabetic peripheral neuropathy.
Hormones (Athens, Greece)
Zhang T,Zhang D,Zhang Z,Tian J,An J,Zhang W,Ben Y
Wed Mar 01 00:00:00 UTC 2023
Alpha-lipoic acid activates AMPK to protect against oxidative stress and apoptosis in rats with diabetic peripheral neuropathy.
Hormones (Athens, Greece)
Zhang T,Zhang D,Zhang Z,Tian J,An J,Zhang W,Ben Y
Wed Mar 01 00:00:00 UTC 2023
Role of Nrf2 in 1,2-dichloropropane-induced cell proliferation and DNA damage in the mouse liver.
Toxicological sciences : an official journal of the Society of Toxicology
Kimura Y,Ekuban FA,Zong C,Sugie S,Zhang X,Itoh K,Yamamoto M,Ichihara S,Ohsako S,Ichihara G
Tue Aug 29 00:00:00 UTC 2023
Triterpenoids from Uncaria macrophylla as ferroptosis inhibitors.
Phytochemistry
Liang X,Wei Y,Hou X,Guo Q,Liang H,Zeng K,Tu P,Zhang Q
Wed Feb 01 00:00:00 UTC 2023
A Rational Design of Metal-Organic Framework Nanozyme with High-Performance Copper Active Centers for Alleviating Chemical Corneal Burns.
Nano-micro letters
Tang Y,Han Y,Zhao J,Lv Y,Fan C,Zheng L,Zhang Z,Liu Z,Li C,Lin Y
Sun Apr 30 00:00:00 UTC 2023
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
Journal of medicinal chemistry
Qi M,Zhong H,Cheng Z,Chen S,Xiao H,Shang J,Chen L,Sun J
Thu Jul 13 00:00:00 UTC 2023
Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
Journal of medicinal chemistry
Qi M,Zhong H,Cheng Z,Chen S,Xiao H,Shang J,Chen L,Sun J
Thu Jul 13 00:00:00 UTC 2023
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
The American journal of Chinese medicine
Li Q,Li Z,Liu C,Xu M,Li T,Wang Y,Feng J,Yin X,Du X,Lu C
Mon Jun 19 00:00:00 UTC 2023
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Frontiers in pharmacology
Lou L,Wang M,He J,Yang S,Meng F,Wang S,Jin X,Cai J,Cai C
Tue Mar 28 00:00:00 UTC 2023
Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway.
International immunopharmacology
Li X,Yu X,He S,Li J
Sat Jul 01 00:00:00 UTC 2023
ARE-PROTACs Enable Co-degradation of an Nrf2-MafG Heterodimer.
Journal of medicinal chemistry
Ji J,Ma S,Zhu Y,Zhao J,Tong Y,You Q,Jiang Z
Thu May 11 00:00:00 UTC 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 UTC 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 UTC 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 UTC 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 UTC 2023
Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway.
ACS pharmacology & translational science
Wang F,Zhan Y,Li M,Wang L,Zheng A,Liu C,Wang H,Wang T
Fri Jan 13 00:00:00 UTC 2023
A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression.
Nature cancer
Culbertson B,Garcia K,Markett D,Asgharian H,Chen L,Fish L,Navickas A,Yu J,Woo B,Nanda AS,Choi B,Zhou S,Rabinowitz J,Goodarzi H
Mon May 01 00:00:00 UTC 2023
A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression.
Nature cancer
Culbertson B,Garcia K,Markett D,Asgharian H,Chen L,Fish L,Navickas A,Yu J,Woo B,Nanda AS,Choi B,Zhou S,Rabinowitz J,Goodarzi H
Mon May 01 00:00:00 UTC 2023
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells.
Tissue engineering and regenerative medicine
Zhang Y,Wang P,Jin MX,Zhou YQ,Ye L,Zhu XJ,Li HF,Zhou M,Li Y,Li S,Liang KY,Wang Y,Gao Y,Pan MX,Zhou SQ,Peng Q
Thu Jun 01 00:00:00 UTC 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 UTC 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 UTC 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 UTC 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 UTC 2023
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
International immunopharmacology
Zhu D,Kong M,Chen C,Luo J,Kong L
Wed Feb 01 00:00:00 UTC 2023
Dental Pulp Stem Cells Ameliorate Elastase-Induced Pulmonary Emphysema by Regulating Inflammation and Oxidative Stress.
Journal of inflammation research
Gao X,Liu Z,Wang Z
Tue Apr 18 00:00:00 UTC 2023
Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss.
International immunopharmacology
Guo J,Ren R,Guo Z,Sun K,He J,Shao J,Wang X
Wed Mar 01 00:00:00 UTC 2023
Ro25-6981 alleviates neuronal damage and improves cognitive deficits by attenuating oxidative stress via the Nrf2/ARE pathway in ischemia/reperfusion rats.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Gao X,Chen F,Xu X,Liu J,Dong F,Liu Y
Wed Mar 01 00:00:00 UTC 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 UTC 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 UTC 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 UTC 2023
Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells.
Biochemical and biophysical research communications
Ma B,Zhong Y,Chen R,Zhan X,Huang G,Xiong Y,Tan B
Wed Jul 12 00:00:00 UTC 2023
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hu Y,Yan Z,He Y,Li Y,Li M,Li Y,Zhang D,Zhao Y,Ommati MM,Wang J,Huo M,Wang J
Sat Apr 01 00:00:00 UTC 2023
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Free radical biology & medicine
Zhang Z,Cheng J,Yang L,Li X,Hua R,Xu D,Jiang Z,Li Q
Mon May 01 00:00:00 UTC 2023
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Journal of animal science and biotechnology
Shao D,Shen W,Miao Y,Gao Z,Pan M,Wei Q,Yan Z,Zhao X,Ma B
Wed May 03 00:00:00 UTC 2023
Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP+-Induced SH-SY5Y Cells.
Neurotoxicity research
Lai X,Zhang Y,Wu J,Shen M,Yin S,Yan J
Thu Jun 01 00:00:00 UTC 2023
Sulforaphane Suppresses H2O2-Induced Oxidative Stress and Apoptosis via the Activation of AMPK/NFE2L2 Signaling Pathway in Goat Mammary Epithelial Cells.
International journal of molecular sciences
Shao D,Gao Z,Zhao Y,Fan M,Zhao X,Wei Q,Pan M,Ma B
Thu Jan 05 00:00:00 UTC 2023
Pharmacological network analysis of the functions and mechanism of kaempferol from Du Zhong in intervertebral disc degeneration (IDD).
Journal of orthopaedic translation
Wang X,Tan Y,Liu F,Wang J,Liu F,Zhang Q,Li J
Wed Mar 01 00:00:00 UTC 2023
Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt-GSK-3β-Nrf2 pathway.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Liu X,Liu Y,Chen L,Zhang Z,Cui L,Wei T
Wed Mar 01 00:00:00 UTC 2023
Andrographolide protects bone marrow mesenchymal stem cells against glucose and serum deprivation under hypoxia via the NRF2 signaling pathway.
Stem cell research & therapy
Sun Y,Xu H,Tan B,Yi Q,Liu H,Chen T,Xiang H,Wang R,Xie Q,Tian J,Zhu J
Mon Jul 18 00:00:00 UTC 2022
Total terpenoids of Inula japonica activated the Nrf2 receptor to alleviate the inflammation and oxidative stress in LPS-induced acute lung injury.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang J,Zhang M,Zhang WH,Zhu QM,Ning J,Huo XK,Xiao HT,Sun CP
Thu Dec 01 00:00:00 UTC 2022
Flavokawain A alleviates the progression of mouse osteoarthritis: An in vitro and in vivo study.
Frontiers in bioengineering and biotechnology
Jing S,Wan J,Wang T,He Z,Ding Q,Sheng G,Wang S,Zhao H,Zhu Z,Wu H,Li W
Fri Dec 23 00:00:00 UTC 2022
Relationship between Neuroprotective Effects and Structure of Procyanidins.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Apr 02 00:00:00 UTC 2022
Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects.
Journal of medicinal chemistry
He ZX,An Q,Wei B,Zhou WJ,Wei BF,Gong YP,Zhang X,Gao G,Dong GJ,Huo JL,Zhang XH,Yang FF,Liu HM,Ma LY,Zhao W
Thu Jan 13 00:00:00 UTC 2022
GRP78 Antibodies Are Associated With Blood-Brain Barrier Breakdown in Anti-Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disorder.
Neurology(R) neuroimmunology & neuroinflammation
Shimizu F,Ogawa R,Mizukami Y,Watanabe K,Hara K,Kadono C,Takahashi T,Misu T,Takeshita Y,Sano Y,Fujisawa M,Maeda T,Nakashima I,Fujihara K,Kanda T
Sat Jan 01 00:00:00 UTC 2022
Psoralen alleviates radiation-induced bone injury by rescuing skeletal stem cell stemness through AKT-mediated upregulation of GSK-3β and NRF2.
Stem cell research & therapy
Yin BF,Li ZL,Yan ZQ,Guo Z,Liang JW,Wang Q,Zhao ZD,Li PL,Hao RC,Han MY,Li XT,Mao N,Ding L,Chen DF,Gao Y,Zhu H
Tue Jun 07 00:00:00 UTC 2022
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Journal of dental sciences
Xi X,Li ZX,Zhao Y,Liu H,Chen S,Liu DX
Fri Apr 01 00:00:00 UTC 2022
Sauchinone alleviates dextran sulfate sodium-induced ulcerative colitis via NAD(P)H dehydrogenase [quinone] 1/NF-kB pathway and gut microbiota.
Frontiers in microbiology
Wu K,Liu X,Meng X,Cao L,Li H,Bi Y,Wang M,Wang M,Jiang Y
Thu Feb 02 00:00:00 UTC 2023
4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis.
International journal of biological sciences
Zhang P,Wang Y,Yang W,Yin Y,Li C,Ma X,Shi L,Li R,Tao K
Mon Dec 12 00:00:00 UTC 2022
Neuroprotective effect of Ginsenoside Re against neurotoxin‑induced Parkinson's disease models via induction of Nrf2.
Molecular medicine reports
Qiao J,Zhao Y,Liu Y,Zhang S,Zhao W,Liu S,Liu M
Wed Jun 01 00:00:00 UTC 2022
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy.
Journal of translational medicine
Qiu D,Song S,Wang Y,Bian Y,Wu M,Wu H,Shi Y,Duan H
Fri Jan 28 00:00:00 UTC 2022
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy.
Journal of translational medicine
Qiu D,Song S,Wang Y,Bian Y,Wu M,Wu H,Shi Y,Duan H
Fri Jan 28 00:00:00 UTC 2022
Berberine prevents lethal EV71 neurological infection in newborn mice.
Frontiers in pharmacology
Cui G,Wang H,Yang C,Zhou X,Wang J,Wang T,Ma T
Fri Nov 18 00:00:00 UTC 2022
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
Cell death discovery
Ma H,Xie C,Chen Z,He G,Dai Z,Cai H,Zhang H,Lu H,Wu H,Hu X,Zhou K,Zheng G,Xu H,Xu C
Tue Apr 19 00:00:00 UTC 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 UTC 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 UTC 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 UTC 2022
Lipoxin A4 and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway.
Experimental cell research
Xu F,Zhang J,Zhou X,Hao H
Tue Mar 01 00:00:00 UTC 2022
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Frontiers in pharmacology
Wang J,Wang K,Ding L,Zhao P,Zhang C,Wang H,Yang Z,Liu Z
Tue Sep 03 00:00:00 UTC 2024
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kang H,Guo Q,Dong Y,Peng R,Song K,Wang J,Liu H,Zhu M,Zhao H,Guan H,Li F
Tue Feb 01 00:00:00 UTC 2022
MicroRNA-141-3p attenuates oxidative stress-induced hepatic ischemia reperfusion injury via Keap1/Nrf2 pathway.
Molecular biology reports
Li T,Chen Q,Dai J,Huang Z,Luo Y,Mou T,Pu J,Yang H,Wei X,Wu Z
Mon Aug 01 00:00:00 UTC 2022
Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury.
Antioxidants (Basel, Switzerland)
Bondi CD,Rush BM,Hartman HL,Wang J,Al-Bataineh MM,Hughey RP,Tan RJ
Wed Sep 14 00:00:00 UTC 2022
Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury.
Antioxidants (Basel, Switzerland)
Bondi CD,Rush BM,Hartman HL,Wang J,Al-Bataineh MM,Hughey RP,Tan RJ
Wed Sep 14 00:00:00 UTC 2022
Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury.
Antioxidants (Basel, Switzerland)
Bondi CD,Rush BM,Hartman HL,Wang J,Al-Bataineh MM,Hughey RP,Tan RJ
Wed Sep 14 00:00:00 UTC 2022
Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury.
Antioxidants (Basel, Switzerland)
Bondi CD,Rush BM,Hartman HL,Wang J,Al-Bataineh MM,Hughey RP,Tan RJ
Wed Sep 14 00:00:00 UTC 2022
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Biochemical pharmacology
Kang H,Dong Y,Peng R,Liu H,Guo Q,Song K,Zhu M,Yu K,Wu W,Li F
Tue Mar 01 00:00:00 UTC 2022
4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.
Free radical biology & medicine
Peng X,Su S,Zeng J,Xie K,Yang X,Xian G,Xiao Z,Zhu P,Zheng S,Xu D,Zeng Q
Mon Aug 01 00:00:00 UTC 2022
Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo.
Frontiers in pharmacology
Jiang Z,Qi G,Lu W,Wang H,Li D,Chen W,Ding L,Yang X,Yuan H,Zeng Q
Sat Oct 15 00:00:00 UTC 2022
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Theriogenology
Shi L,Wang X,Duan Y,Li K,Ren Y
Wed Jun 01 00:00:00 UTC 2022
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Journal of animal science
Yu G,Ji S,Yun Y,Cheng K,Zhang H,Jia P,Wang T,Zhang L
Fri Jul 01 00:00:00 UTC 2022
Effect and mechanism of TFEB on pyroptosis in HK-2 cells induced by high glucose.
Biochemical and biophysical research communications
Han N,Wang Z,Luo H,Chi Y,Zhang T,Wang B,Li Y
Sat Jun 25 00:00:00 UTC 2022
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Translational neuroscience
Huang L,Han Y,Zhou Q,Sun Z,Yan J
Sat Jan 01 00:00:00 UTC 2022
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway.
Free radical research
Qi Y,Fu S,Pei D,Fang Q,Xin W,Yuan X,Cao Y,Shu Q,Mi X,Luo F
Tue Feb 01 00:00:00 UTC 2022
Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease.
Antioxidants (Basel, Switzerland)
Zhao H,Xian G,Zeng J,Zhong G,An D,Peng Y,Hu D,Lin Y,Li J,Su S,Ning Y,Xu D,Zeng Q
Mon Oct 24 00:00:00 UTC 2022
Collagen peptides from Acaudina molpadioides prevent CCl4 -induced liver injury via Keap1/Nrf2-ARE, PI3K/AKT, and MAPKs pathways.
Journal of food science
Li J,Li Y,Lin S,Zhao W,Chen Y,Jin H
Sun May 01 00:00:00 UTC 2022
Protective effect of resveratrol against hydrogen peroxide-induced oxidative stress in bovine skeletal muscle cells.
Meat science
Zhang X,Liu X,Wan F,You W,Tan X,Sheng Q,Li C,Hu Z,Liu G,Zhao H
Tue Mar 01 00:00:00 UTC 2022
Centrosomal protein 290 is a novel prognostic indicator that modulates liver cancer cell ferroptosis via the Nrf2 pathway.
Aging
Shan Y,Yang G,Lu Q,Hu X,Qi D,Zhou Y,Xiao Y,Cao L,Tian F,Pan Q
Thu Mar 10 00:00:00 UTC 2022
Cyclo(-Phe-Phe) alleviates chick embryo liver injury via activating the Nrf2 pathway.
Food & function
Zhang QY,Han SC,Huang RP,Jiang MY,Yan CY,Li XY,Zhan YJ,Li XM,Li YF,Kurihara H,Tan RR,Li WX,He RR
Mon Jul 04 00:00:00 UTC 2022
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Bioengineered
Zhu W,Tang H,Li J,Guedes RM,Cao L,Guo C
Fri Apr 01 00:00:00 UTC 2022
Acute lung inflammation induced by zinc oxide nanoparticles: Evolution and intervention via NRF2 activator.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Guo T,Fang X,Liu Y,Ruan Y,Hu Y,Wang X,Hu Y,Wang G,Xu Y
Fri Apr 01 00:00:00 UTC 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 UTC 2022
Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat.
Brain research bulletin
Zhou Y,Peng L,Li Y,Zhao Y
Sat Jan 01 00:00:00 UTC 2022
Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma.
Frontiers in pharmacology
Xiu Z,Zhu Y,Han J,Li Y,Yang X,Yang G,Song G,Li S,Li Y,Cheng C,Li Y,Fang J,Li X,Jin N
Fri Jul 29 00:00:00 UTC 2022
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Chemical biology & drug design
Zhu W,Tang H,Cao L,Zhang J,Li J,Ma D,Guo C
Fri Jul 01 00:00:00 UTC 2022
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Journal of animal science and biotechnology
Tian S,Wang J,Gao R,Wang J,Zhu W
Fri Jun 03 00:00:00 UTC 2022
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Ecotoxicology and environmental safety
Liu F,Wang Y,Chen L,Bello BK,Zhang T,Yang H,Li X,Pan E,Feng H,Dong J
Sat Oct 01 00:00:00 UTC 2022
Antioxidant potential of Pediococcus pentosaceus strains from the sow milk bacterial collection in weaned piglets.
Microbiome
Wang L,Liu Q,Chen Y,Zheng X,Wang C,Qi Y,Dong Y,Xiao Y,Chen C,Chen T,Huang Q,Zhai Z,Long C,Yang H,Li J,Wang L,Zhang G,Liao P,Liu YX,Huang P,Huang J,Wang Q,Chu H,Yin J,Yin Y
Wed Jun 01 00:00:00 UTC 2022
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson's Disease Model.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Aug 06 00:00:00 UTC 2022
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Oncology reports
Wang T,Liu J,Huang X,Zhang C,Shangguan M,Chen J,Wu S,Chen M,Yang Z,Zhao S
Tue Nov 01 00:00:00 UTC 2022
Ellagic Acid Alleviates Oxidative Stress by Mediating Nrf2 Signaling Pathways and Protects against Paraquat-Induced Intestinal Injury in Piglets.
Antioxidants (Basel, Switzerland)
Xiao Y,Huang R,Wang N,Deng Y,Tan B,Yin Y,Qi M,Wang J
Thu Jan 27 00:00:00 UTC 2022
Tanshinone IIA Regulates Keap1/Nrf2 Signal Pathway by Activating Sestrin2 to Restrain Pulmonary Fibrosis.
The American journal of Chinese medicine
Li H,Wu M,Guo C,Zhai R,Chen J
Thu Dec 29 00:00:00 UTC 2022
Activation of the P62-Keap1-NRF2 Pathway Protects against Ferroptosis in Radiation-Induced Lung Injury.
Oxidative medicine and cellular longevity
Li X,Chen J,Yuan S,Zhuang X,Qiao T
Mon Dec 12 00:00:00 UTC 2022
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.
Nature communications
Wang X,Liu Y,Xue C,Hu Y,Zhao Y,Cai K,Li M,Luo Z
Wed Sep 28 00:00:00 UTC 2022
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Zhou W,Dong G,Gao G,He Z,Xu J,Aziz S,Ma L,Zhao W
Mon Aug 01 00:00:00 UTC 2022
Streptococcus lutetiensis Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells.
Oxidative medicine and cellular longevity
Chen P,Yang J,Wu N,Han B,Kastelic JP,Gao J
Fri Mar 18 00:00:00 UTC 2022
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology
Zhou X,Wang S,Zhou R,Zhang T,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhou X,Song N
Wed Jun 15 00:00:00 UTC 2022
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology
Zhou X,Wang S,Zhou R,Zhang T,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhou X,Song N
Wed Jun 15 00:00:00 UTC 2022
Dietary Selenium Alleviated Mouse Liver Oxidative Stress and NAFLD Induced by Obesity by Regulating the KEAP1/NRF2 Pathway.
Antioxidants (Basel, Switzerland)
Wang Y,Liu B,Wu P,Chu Y,Gui S,Zheng Y,Chen X
Thu Feb 10 00:00:00 UTC 2022
Type 2 Diabetes Mellitus Makes Corneal Endothelial Cells Vulnerable to Ultraviolet A-Induced Oxidative Damage Via Decreased DJ-1/Nrf2/NQO1 Pathway.
Investigative ophthalmology & visual science
Zhang X,Qiu J,Huang F,Shan K,Zhang C
Tue Nov 01 00:00:00 UTC 2022
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets.
Life sciences
Yao Y,Wang H,Yang Y,Jiang Z,Ma H
Tue Nov 01 00:00:00 UTC 2022
Protection of Human Lens Epithelial Cells from Oxidative Stress Damage and Cell Apoptosis by KGF-2 through the Akt/Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Liu S,Jin Z,Xia R,Zheng Z,Zha Y,Wang Q,Wan X,Yang H,Cai J
Thu Mar 17 00:00:00 UTC 2022
6-methoxyflavone suppresses neuroinflammation in lipopolysaccharide- stimulated microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF-κB dependent pathways and the activation of HO-1/NQO-1 signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen WF,Shih YH,Liu HC,Cheng CI,Chang CI,Chen CY,Lin IP,Lin MY,Lee CH
Sun May 01 00:00:00 UTC 2022
Mesenchymal stem cells improve redox homeostasis and mitochondrial respiration in fibroblast cell lines with pathogenic MT-ND3 and MT-ND6 variants.
Stem cell research & therapy
Navaratnarajah T,Bellmann M,Seibt A,Anand R,Degistirici Ö,Meisel R,Mayatepek E,Reichert A,Baertling F,Distelmaier F
Fri Jun 17 00:00:00 UTC 2022
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
European journal of pharmacology
Zheng LY,Zou X,Wang YL,Zou M,Ma F,Wang N,Li JW,Wang MS,Hung HY,Wang Q
Wed Jan 05 00:00:00 UTC 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 UTC 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 UTC 2022
LipoxinA4 analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
International immunopharmacology
Hao H,Xie F,Xu F,Wang Q,Wu Y,Zhang D
Sat Oct 01 00:00:00 UTC 2022
Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling.
Molecular cell
Fiore A,Zeitler L,Russier M,Groß A,Hiller MK,Parker JL,Stier L,Köcher T,Newstead S,Murray PJ
Thu Mar 03 00:00:00 UTC 2022
Total flavonoids of Inula japonica alleviated the inflammatory response and oxidative stress in LPS-induced acute lung injury via inhibiting the sEH activity: Insights from lipid metabolomics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang J,Zhang M,Zhang WH,Zhu QM,Huo XK,Sun CP,Ma XC,Xiao HT
Thu Dec 01 00:00:00 UTC 2022
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
ChemMedChem
Ye H,Ma Z,Liu L,Zhang T,Han Q,Xiang Z,Xia Y,Ke Y,Guan X,Shi Q,Ataullakhanov FI,Panteleev M
Fri Dec 16 00:00:00 UTC 2022
Trimetazidine and exercise offer analogous improvements to the skeletal muscle insulin resistance of mice through Nrf2 signaling.
BMJ open diabetes research & care
Zhang W,Dun Y,You B,Qiu L,Ripley-Gonzalez JW,Cheng J,Fu S,Li C,Liu S
Tue Mar 01 00:00:00 UTC 2022
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Technology and health care : official journal of the European Society for Engineering and Medicine
Li Y,Chandra TP,Song X,Nie L,Liu M,Yi J,Zheng X,Chu C,Yang J
Wed Aug 18 00:00:00 UTC 2021
Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo.
Journal of inflammation research
Wang H,Jiang Z,Pang Z,Qi G,Hua B,Yan Z,Yuan H
Thu Apr 21 00:00:00 UTC 2022
Baicalin-loaded macrophage-derived exosomes ameliorate ischemic brain injury via the antioxidative pathway.
Materials science & engineering. C, Materials for biological applications
Huang Z,Guo L,Huang L,Shi Y,Liang J,Zhao L
Thu Jul 01 00:00:00 UTC 2021
Design, Synthesis, and Biological Evaluation of a Novel Aminothiol Compound as Potential Radioprotector.
Oxidative medicine and cellular longevity
Li X,Wang X,Miao L,Guo Y,Yuan R,Ren J,Huang Y,Tian H
Fri Jan 28 00:00:00 UTC 2022
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Drug design, development and therapy
Pang Z,Jiang Z,Zhu R,Song C,Tang H,Cao L,Guo C
Thu Jan 20 00:00:00 UTC 2022
Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation.
eLife
Lei I,Tian S,Gao W,Liu L,Guo Y,Tang P,Chen E,Wang Z
Thu Dec 23 00:00:00 UTC 2021
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway.
Journal of ethnopharmacology
Lu Q,Gu W,Luo C,Wang L,Hua W,Sun Y,Tang L
Wed Feb 10 00:00:00 UTC 2021
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Journal of animal science and biotechnology
Chen Y,Zhang H,Chen Y,Jia P,Ji S,Zhang Y,Wang T
Thu Jun 10 00:00:00 UTC 2021
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Toxicology
Liu Z,He Q,Liu Y,Zhang Y,Cui M,Peng H,Wang Y,Chen S,Li D,Chen L,Xiao Y,Chen W,Wang Q
Wed Jun 30 00:00:00 UTC 2021
Protection of the enhanced Nrf2 deacetylation and its downstream transcriptional activity by SIRT1 in myocardial ischemia/reperfusion injury.
International journal of cardiology
Xu JJ,Cui J,Lin Q,Chen XY,Zhang J,Gao EH,Wei B,Zhao W
Mon Nov 01 00:00:00 UTC 2021
The novel nanocomplexes containing deoxycholic acid-grafted chitosan and oleanolic acid displays the hepatoprotective effect against CCl4-induced liver injury in vivo.
International journal of biological macromolecules
Xin C,Liu S,Qu H,Wang Z
Tue Aug 31 00:00:00 UTC 2021
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Cell proliferation
Xu Y,Sang W,Zhong Y,Xue S,Yang M,Wang C,Lu H,Huan R,Mao X,Zhu L,He C,Ma J
Wed Dec 01 00:00:00 UTC 2021
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
Brain research bulletin
Hou X,Liu H,Ping Y,Zhang F,Zhi L,Jiang X,Zhang F,Song C,Zhang Z,Song J
Sun Aug 01 00:00:00 UTC 2021
Sestrin2 protects against traumatic brain injury by reinforcing the activation of Nrf2 signaling.
Human & experimental toxicology
Liu X,Li M,Zhu J,Huang W,Song J
Thu Jul 01 00:00:00 UTC 2021
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
International immunopharmacology
Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q
Mon Nov 01 00:00:00 UTC 2021
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Experimental cell research
Xi X,Zhao Y,Liu H,Li Z,Chen S,Liu D
Tue Jun 15 00:00:00 UTC 2021
Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway.
Ecotoxicology and environmental safety
Li S,Wang X,Xiao Y,Wang Y,Wan Y,Li X,Li Q,Tang X,Cai D,Ran B,Wu C
Fri Jan 15 00:00:00 UTC 2021
Tolerable upper intake level of iron damages the liver of weaned piglets.
Journal of animal physiology and animal nutrition
Ding H,Zhao Y,Yu X,Chen L,Han J,Feng J
Thu Jul 01 00:00:00 UTC 2021
Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation.
Antioxidants (Basel, Switzerland)
Cores Á,Abril S,Michalska P,Duarte P,Olives AI,Martín MA,Villacampa M,León R,Menéndez JC
Thu Jun 10 00:00:00 UTC 2021
SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production.
Frontiers in cell and developmental biology
Zhao X,Gao M,Liang J,Chen Y,Wang Y,Wang Y,Xiao Y,Zhao Z,Wan X,Jiang M,Luo X,Wang F,Sun X
Wed Mar 10 00:00:00 UTC 2021
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
International journal of biological macromolecules
Liu C,Hua H,Zhu H,Cheng Y,Guo Y,Yao W,Qian H
Tue Aug 31 00:00:00 UTC 2021
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation.
Toxicology
Shao Y,Wang X,Zhou Y,Jiang Y,Wu R,Lu C
Wed Sep 01 00:00:00 UTC 2021
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
International immunopharmacology
Xun W,Fu Q,Shi L,Cao T,Jiang H,Ma Z
Fri Oct 01 00:00:00 UTC 2021
Peptides Isolated from Yak Milk Residue Exert Antioxidant Effects through Nrf2 Signal Pathway.
Oxidative medicine and cellular longevity
Yang F,He X,Chen T,Liu J,Luo Z,Sun S,Qin D,Huang W,Tang Y,Liu C,Luo F
Fri Mar 04 00:00:00 UTC 2022
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
Frontiers in physiology
Xu Q,Li S,Tang W,Yan J,Wei X,Zhou M,Diao H
Tue Oct 26 00:00:00 UTC 2021
ARNT deficiency represses pyruvate dehydrogenase kinase 1 to trigger ROS production and melanoma metastasis.
Oncogenesis
Huang CR,Chang TW,Lee CT,Shen CJ,Chang WC,Chen BK
Thu Jan 14 00:00:00 UTC 2021
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Frontiers in nutrition
Li X,Gao M,Zhu S,Yin L,Zhang B,Qi Y,Zhao Y,Yu Y,Xu L
Tue Jun 15 00:00:00 UTC 2021
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Oxidative medicine and cellular longevity
Lv D,Luo M,Cheng Z,Wang R,Yang X,Guo Y,Huang L,Li X,Huang B,Shen J,Luo S,Yan J
Mon Feb 07 00:00:00 UTC 2022
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Food & function
Liu XL,Zhao YC,Zhu HY,Wu M,Zheng YN,Yang M,Cheng ZQ,Ding CB,Liu WC
Mon Nov 29 00:00:00 UTC 2021
Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway.
Journal of immunology research
Lin Y,Xie Y,Hao Z,Bi H,Liu Y,Yang X,Xia Y
Thu Mar 03 00:00:00 UTC 2022
Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
Free radical biology & medicine
Wang Z,Cai B,Cao C,Lv H,Dai Y,Zheng M,Zhao G,Peng Y,Gou W,Wang J,Liu D,Hu Y
Sat Feb 20 00:00:00 UTC 2021
Tert-Butylhydroquinone Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in Rat Chondrocytes.
Evidence-based complementary and alternative medicine : eCAM
Yang B,Huang H,He Q,Lu W,Zheng L,Cui L
Tue Dec 21 00:00:00 UTC 2021
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Journal of agricultural and food chemistry
Xing Y,Ren X,Li X,Sui L,Shi X,Sun Y,Quan C,Xiu Z,Dong Y
Wed Sep 01 00:00:00 UTC 2021
Curcumin activates Nrf2 through PKCδ-mediated p62 phosphorylation at Ser351.
Scientific reports
Park JY,Sohn HY,Koh YH,Jo C
Mon Apr 19 00:00:00 UTC 2021
In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Feng XH,Xu HY,Wang JY,Duan S,Wang YC,Ma CM
Mon Mar 01 00:00:00 UTC 2021
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Aging
Yang RZ,Zheng HL,Xu WN,Zheng XF,Li B,Jiang LS,Jiang SD
Mon Feb 01 00:00:00 UTC 2021
Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.
Cell death discovery
Zhu J,Li X,Liang C,Zhou X,Ge M,Chen Y,Jin J,Yin J,Xu H,Xie C,Zhong C
Wed May 12 00:00:00 UTC 2021
Reparative Effects of Ethanol-Induced Intestinal Barrier Injury by Flavonoid Luteolin via MAPK/NF-κB/MLCK and Nrf2 Signaling Pathways.
Journal of agricultural and food chemistry
Yuan J,Che S,Zhang L,Ruan Z
Wed Apr 14 00:00:00 UTC 2021
PDE9 Inhibitor PF-04447943 Attenuates DSS-Induced Colitis by Suppressing Oxidative Stress, Inflammation, and Regulating T-Cell Polarization.
Frontiers in pharmacology
Rana MN,Lu J,Xue E,Ruan J,Liu Y,Zhang L,Dhar R,Li Y,Hu Z,Zhou J,Ma W,Tang H
Wed May 22 00:00:00 UTC 2024
RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.
Cell death & disease
Feng X,Jiang T,Yang C,Pang S,Ding Z,Hu H,Wang H,Dong L,Yang N
Fri Dec 17 00:00:00 UTC 2021
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Medical science monitor : international medical journal of experimental and clinical research
Pan H,Xu Y,Cai Q,Wu M,Ding M
Fri Jun 04 00:00:00 UTC 2021
Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J,Li D
Mon May 17 00:00:00 UTC 2021
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Food chemistry
Wang Y,Jin R,Chen J,Cao J,Xiao J,Li X,Sun C
Wed Dec 15 00:00:00 UTC 2021
Nano chitosan-zinc complex improves the growth performance and antioxidant capacity of the small intestine in weaned piglets.
The British journal of nutrition
Zhang M,Hou G,Hu P,Feng D,Wang J,Zhu W
Tue Sep 28 00:00:00 UTC 2021
PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis.
Environmental toxicology
Meng X,Zhang L,Han B,Zhang Z
Mon Nov 01 00:00:00 UTC 2021
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Cell death discovery
Wang W,Zhai D,Bai Y,Xue K,Deng L,Ma L,Du T,Ye Z,Qu D,Xiang A,Chen G,Zhao Y,Wang L,Lu Z
Tue Mar 23 00:00:00 UTC 2021
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Ecotoxicology and environmental safety
Zhao G,Qi L,Wang Y,Li X,Li Q,Tang X,Wang X,Wu C
Fri Oct 01 00:00:00 UTC 2021
4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response.
Frontiers in pharmacology
Li R,Yang W,Yin Y,Ma X,Zhang P,Tao K
Sat Jun 12 00:00:00 UTC 2021
Exosomes are involved in total body irradiation-induced intestinal injury in mice.
Acta pharmacologica Sinica
Li H,Jiang M,Zhao SY,Zhang SQ,Lu L,He X,Feng GX,Wu X,Fan SJ
Thu Jul 01 00:00:00 UTC 2021
Regulatory effects of flavonoids luteolin on BDE-209-induced intestinal epithelial barrier damage in Caco-2 cell monolayer model.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yuan J,Che S,Ruan Z,Song L,Tang R,Zhang L
Thu Apr 01 00:00:00 UTC 2021
Protective effect of limonin against doxorubicin-induced cardiotoxicity via activating nuclear factor - like 2 and Sirtuin 2 signaling pathways.
Bioengineered
Deng J,Huang M,Wu H
Wed Dec 01 00:00:00 UTC 2021
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Free radical biology & medicine
Ma WQ,Sun XJ,Zhu Y,Liu NF
Mon Mar 01 00:00:00 UTC 2021
CPSF6 links alternative polyadenylation to metabolism adaption in hepatocellular carcinoma progression.
Journal of experimental & clinical cancer research : CR
Tan S,Zhang M,Shi X,Ding K,Zhao Q,Guo Q,Wang H,Wu Z,Kang Y,Zhu T,Sun J,Zhao X
Mon Mar 01 00:00:00 UTC 2021
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Autophagy
Deng Z,Lim J,Wang Q,Purtell K,Wu S,Palomo GM,Tan H,Manfredi G,Zhao Y,Peng J,Hu B,Chen S,Yue Z
Fri May 01 00:00:00 UTC 2020
Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Wang J,Fang Z,Song C,Kang H,Guo Q,Dong Y,Zhang Y,Peng R,Guan H,Li F
Mon Sep 28 00:00:00 UTC 2020
USP9X prevents AGEs-induced upregulation of FN and TGF-β1 through activating Nrf2-ARE pathway in rat glomerular mesangial cells.
Experimental cell research
Huang K,Zhao X
Sat Aug 15 00:00:00 UTC 2020
Dietary Supplemented Curcumin Improves Meat Quality and Antioxidant Status of Intrauterine Growth Retardation Growing Pigs via Nrf2 Signal Pathway.
Animals : an open access journal from MDPI
Zhang L,Zhang J,Yan E,He J,Zhong X,Zhang L,Wang C,Wang T
Tue Mar 24 00:00:00 UTC 2020
Long noncoding RNA TUG1 regulates prostate cancer cell proliferation, invasion and migration via the Nrf2 signaling axis.
Pathology, research and practice
Yang G,Yin H,Lin F,Gao S,Zhan K,Tong H,Tang X,Pan Q,Gou X
Wed Apr 01 00:00:00 UTC 2020
Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.
Molecular cancer research : MCR
Song S,Nguyen V,Schrank T,Mulvaney K,Walter V,Wei D,Orvis T,Desai N,Zhang J,Hayes DN,Zheng Y,Major MB,Weissman BE
Tue Dec 01 00:00:00 UTC 2020
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression.
Acta biochimica et biophysica Sinica
Chen X,Qi J,Wu Q,Jiang H,Wang J,Chen W,Mao A,Zhu M
Tue May 26 00:00:00 UTC 2020
Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo.
Drug design, development and therapy
Wang H,Jiang Z,Pang Z,Zhou T,Gu Y
Mon Aug 23 00:00:00 UTC 2021
Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice.
Scientific reports
Tamatam CM,Reddy NM,Potteti HR,Ankireddy A,Noone PM,Yamamoto M,Kensler TW,Reddy SP
Wed Nov 04 00:00:00 UTC 2020
Four active monomers from Moutan Cortex exert inhibitory effects against oxidative stress by activating Nrf2/Keap1 signaling pathway.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhang B,Yu D,Luo N,Yang C,Zhu Y
Tue Sep 01 00:00:00 UTC 2020
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
International journal of molecular sciences
Wang S,Cheng H,Wang L,Zhao R,Guan D
Mon Mar 16 00:00:00 UTC 2020
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Journal of food biochemistry
Wang Z,Cai L,Li H,Liang M,Zhang Y,Wu Q,Yang L
Fri May 01 00:00:00 UTC 2020
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Nature communications
Choi I,Zhang Y,Seegobin SP,Pruvost M,Wang Q,Purtell K,Zhang B,Yue Z
Fri Mar 13 00:00:00 UTC 2020
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway.
Antioxidants (Basel, Switzerland)
Qi L,Jiang J,Zhang J,Zhang L,Wang T
Sat Feb 01 00:00:00 UTC 2020
The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance.
Cell proliferation
Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X
Sun Mar 01 00:00:00 UTC 2020
NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis.
Cell death & disease
Liu H,Zhu Y,Gao Y,Qi D,Zhao L,Zhao L,Liu C,Tao T,Zhou C,Sun X,Guo F,Xiao J
Tue Feb 18 00:00:00 UTC 2020
Artemisinin attenuates early renal damage on diabetic nephropathy rats through suppressing TGF-β1 regulator and activating the Nrf2 signaling pathway.
Life sciences
Zhang H,Qi S,Song Y,Ling C
Tue Sep 01 00:00:00 UTC 2020
Neuroprotective effect of dimethyl fumarate on cognitive impairment induced by ischemic stroke.
Annals of translational medicine
Hou X,Xu H,Chen W,Zhang N,Zhao Z,Fang X,Zhang X,Chen H,Xu Y
Sun Mar 01 00:00:00 UTC 2020
Protective Effect of Simplicillium sp. Ethyl Acetate Extract against High Glucose-Induced Oxidative Stress in HUVECs.
Evidence-based complementary and alternative medicine : eCAM
Tian TT,Li QR,Gan SQ,Chang CR,Shen XC
Mon Sep 28 00:00:00 UTC 2020
Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses.
Life sciences
Kang L,Liu S,Li J,Tian Y,Xue Y,Liu X
Sat Feb 15 00:00:00 UTC 2020
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Journal of animal science and biotechnology
Zhang H,Chen Y,Chen Y,Ji S,Jia P,Li Y,Wang T
Sat Nov 11 00:00:00 UTC 2023
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Frontiers in pharmacology
Qi D,Liu H,Sun X,Luo D,Zhu M,Tao T,Gao C,Zhou C,Zhou W,Xiao J
Fri Feb 26 00:00:00 UTC 2021
Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy.
Cell death & disease
Xu Q,Shi W,Lv P,Meng W,Mao G,Gong C,Chen Y,Wei Y,He X,Zhao J,Han H,Sun M,Xiao K
Thu Jan 02 00:00:00 UTC 2020
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Biomaterials
Wang T,Jian Z,Baskys A,Yang J,Li J,Guo H,Hei Y,Xian P,He Z,Li Z,Li N,Long Q
Thu Oct 01 00:00:00 UTC 2020
Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease.
Science translational medicine
Lu Y,Sun Y,Liu Z,Lu Y,Zhu X,Lan B,Mi Z,Dang L,Li N,Zhan W,Tan L,Pi J,Xiong H,Zhang L,Chen Y
Wed Jul 29 00:00:00 UTC 2020
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhu M,Liu H,Sun K,Liu J,Mou Y,Qi D,Zhou C,Abudunaibi M,Tasiken B,Li J,Cheng H,Huang H
Sun Mar 01 00:00:00 UTC 2020
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Free radical biology & medicine
Zhang P,Yin Y,Wang T,Li W,Li C,Zeng X,Yang W,Zhang R,Tang Y,Shi L,Li R,Tao K
Sat Feb 01 00:00:00 UTC 2020
Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets.
NPJ precision oncology
Sekiguchi M,Seki M,Kawai T,Yoshida K,Yoshida M,Isobe T,Hoshino N,Shirai R,Tanaka M,Souzaki R,Watanabe K,Arakawa Y,Nannya Y,Suzuki H,Fujii Y,Kataoka K,Shiraishi Y,Chiba K,Tanaka H,Shimamura T,Sato Y,Sato-Otsubo A,Kimura S,Kubota Y,Hiwatari M,Koh K,Hayashi Y,Kanamori Y,Kasahara M,Kohashi K,Kato M,Yoshioka T,Matsumoto K,Oka A,Taguchi T,Sanada M,Tanaka Y,Miyano S,Hata K,Ogawa S,Takita J
Wed Jul 07 00:00:00 UTC 2021
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Journal of medicinal food
Li H,Liang M,Wang Z,Zhang Y,Wu Q,Yang L
Mon Jun 01 00:00:00 UTC 2020
Isoquinoline Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-Derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability.
Journal of medicinal chemistry
Lazzara PR,David BP,Ankireddy A,Richardson BG,Dye K,Ratia KM,Reddy SP,Moore TW
Thu Jun 25 00:00:00 UTC 2020
Activating PPARγ Increases NQO1 and γ-GCS Expression via Nrf2 in Thrombin-activated Microglia.
Current medical science
Hang H,Wang LK,Ren SY,Song AJ,Wu GF
Sat Feb 01 00:00:00 UTC 2020
Activating PPARγ Increases NQO1 and γ-GCS Expression via Nrf2 in Thrombin-activated Microglia.
Current medical science
Hang H,Wang LK,Ren SY,Song AJ,Wu GF
Sat Feb 01 00:00:00 UTC 2020
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Antioxidants (Basel, Switzerland)
Sun B,Wang X,Liu X,Wang L,Ren F,Wang X,Leng X
Tue Aug 25 00:00:00 UTC 2020
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 UTC 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 UTC 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 UTC 2019
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Journal of cellular physiology
Liu H,Dong Y,Gao Y,Zhao L,Cai C,Qi D,Zhu M,Zhao L,Liu C,Guo F,Xiao J,Huang H
Mon Jul 01 00:00:00 UTC 2019
Antagonistic effect of epigallocatechin-3-gallate on neurotoxicity induced by formaldehyde.
Toxicology
Huang J,Lu Y,Zhang B,Yang S,Zhang Q,Cui H,Lu X,Zhao Y,Yang X,Li R
Tue Jan 15 00:00:00 UTC 2019
Antagonistic effect of epigallocatechin-3-gallate on neurotoxicity induced by formaldehyde.
Toxicology
Huang J,Lu Y,Zhang B,Yang S,Zhang Q,Cui H,Lu X,Zhao Y,Yang X,Li R
Tue Jan 15 00:00:00 UTC 2019
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Journal of cellular biochemistry
Li Y,Chen Y,Qiu C,Ma X,Lei K,Cai G,Liang X,Liu J
Fri Feb 01 00:00:00 UTC 2019
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Journal of cellular biochemistry
Li Y,Chen Y,Qiu C,Ma X,Lei K,Cai G,Liang X,Liu J
Fri Feb 01 00:00:00 UTC 2019
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Journal of the science of food and agriculture
Wang Z,Liang M,Li H,Cai L,He H,Wu Q,Yang L
Thu Aug 15 00:00:00 UTC 2019
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Pharmacological research
Zhao X,Jin Y,Li L,Xu L,Tang Z,Qi Y,Yin L,Peng J
Thu Aug 01 00:00:00 UTC 2019
Selenepezil, a Selenium-Containing Compound, Exerts Neuroprotective Effect via Modulation of the Keap1-Nrf2-ARE Pathway and Attenuates Aβ-Induced Cognitive Impairment in Vivo.
ACS chemical neuroscience
Yan J,Pang Y,Zhuang J,Lin H,Zhang Q,Han L,Ke P,Zhuang J,Huang X
Wed Jun 19 00:00:00 UTC 2019
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Nature
Bersuker K,Hendricks JM,Li Z,Magtanong L,Ford B,Tang PH,Roberts MA,Tong B,Maimone TJ,Zoncu R,Bassik MC,Nomura DK,Dixon SJ,Olzmann JA
Fri Nov 01 00:00:00 UTC 2019
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents.
Nature communications
Wang Z,Chen Z,Jiang Z,Luo P,Liu L,Huang Y,Wang H,Wang Y,Long L,Tan X,Liu D,Jin T,Wang Y,Wang Y,Liao F,Zhang C,Chen L,Gan Y,Liu Y,Yang F,Huang C,Miao H,Chen J,Cheng T,Fu X,Shi C
Mon Jun 10 00:00:00 UTC 2019
Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
Journal of ethnopharmacology
Lu Q,Tan S,Gu W,Li F,Hua W,Zhang S,Chen F,Tang L
Mon Oct 28 00:00:00 UTC 2019
Curcumin upregulates the Nrf2 system by repressing inflammatory signaling-mediated Keap1 expression in insulin-resistant conditions.
Biochemical and biophysical research communications
Ren L,Zhan P,Wang Q,Wang C,Liu Y,Yu Z,Zhang S
Sun Jun 30 00:00:00 UTC 2019
Astragaloside IV Protects Against Oxidative Stress in Calf Small Intestine Epithelial Cells via NFE2L2-Antioxidant Response Element Signaling.
International journal of molecular sciences
Wang Y,Jiang F,Cheng H,Tan X,Liu Y,Wei C,Song E
Thu Dec 05 00:00:00 UTC 2019
Astragaloside IV Protects Against Oxidative Stress in Calf Small Intestine Epithelial Cells via NFE2L2-Antioxidant Response Element Signaling.
International journal of molecular sciences
Wang Y,Jiang F,Cheng H,Tan X,Liu Y,Wei C,Song E
Thu Dec 05 00:00:00 UTC 2019
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Gao X,Jiang S,Du Z,Ke A,Liang Q,Li X
Mon May 04 00:00:00 UTC 2020
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.
Neurochemical research
Betharia S,Rondόn-Ortiz AN,Brown DA
Thu Aug 01 00:00:00 UTC 2019
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Journal of agricultural and food chemistry
Jia YN,Peng YL,Zhao YP,Cheng XF,Zhou Y,Chai CL,Zeng LS,Pan MH,Xu L
Wed May 15 00:00:00 UTC 2019
Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors.
International journal of molecular sciences
Sparaneo A,Fabrizio FP,la Torre A,Graziano P,Di Maio M,Fontana A,Bisceglia M,Rossi A,Pizzolitto S,De Maglio G,Tancredi A,Grimaldi F,Balsamo T,Centra F,Manzorra MC,Trombetta D,Pantalone A,Bonfitto A,Maiello E,Fazio VM,Muscarella LA
Thu May 23 00:00:00 UTC 2019
Effects of KEAP1 Silencing on the Regulation of NRF2 Activity in Neuroendocrine Lung Tumors.
International journal of molecular sciences
Sparaneo A,Fabrizio FP,la Torre A,Graziano P,Di Maio M,Fontana A,Bisceglia M,Rossi A,Pizzolitto S,De Maglio G,Tancredi A,Grimaldi F,Balsamo T,Centra F,Manzorra MC,Trombetta D,Pantalone A,Bonfitto A,Maiello E,Fazio VM,Muscarella LA
Thu May 23 00:00:00 UTC 2019
Potent 5-Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1-UBE2M Interaction.
Journal of medicinal chemistry
Zhou W,Ma L,Ding L,Guo Q,He Z,Yang J,Qiao H,Li L,Yang J,Yu S,Zhao L,Wang S,Liu HM,Suo Z,Zhao W
Thu Jun 13 00:00:00 UTC 2019
Neuroprotective Effect of Dioscin on the Aging Brain.
Molecules (Basel, Switzerland)
Qi Y,Li R,Xu L,Yin L,Xu Y,Han X,Peng J
Sat Mar 30 00:00:00 UTC 2019
The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice.
Marine drugs
Lin F,Yang D,Huang Y,Zhao Y,Ye J,Xiao M
Fri Sep 20 00:00:00 UTC 2019
NAD(P)H: Quinone oxidoreductase 1 overexpression in hepatocellular carcinoma potentiates apoptosis evasion through regulating stabilization of X-linked inhibitor of apoptosis protein.
Cancer letters
Li WY,Zhou HZ,Chen Y,Cai XF,Tang H,Ren JH,Wai Wong VK,Kwan Law BY,Chen Y,Cheng ST,Yu HB,Cai HY,Chen WX,Tang N,Zhang WL,Tao NN,Yang QX,Ren F,He L,Jiang H,Huang AL,Chen J
Sat Jun 01 00:00:00 UTC 2019
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Free radical biology & medicine
Li AL,Shen T,Wang T,Zhou MX,Wang B,Song JT,Zhang PL,Wang XL,Ren DM,Lou HX,Wang XN
Sun Sep 01 00:00:00 UTC 2019
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Food & function
Shu G,Qiu Y,Hao J,Fu Q,Deng X
Wed Oct 16 00:00:00 UTC 2019
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng L,Yin L,Xu L,Qi Y,Li H,Xu Y,Han X,Liu K,Peng J
Mon Jan 01 00:00:00 UTC 2018
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng L,Yin L,Xu L,Qi Y,Li H,Xu Y,Han X,Liu K,Peng J
Mon Jan 01 00:00:00 UTC 2018
Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.
Biochemical pharmacology
Wang K,Lv Q,Miao YM,Qiao SM,Dai Y,Wei ZF
Sat Sep 01 00:00:00 UTC 2018
Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.
Biochemical pharmacology
Wang K,Lv Q,Miao YM,Qiao SM,Dai Y,Wei ZF
Sat Sep 01 00:00:00 UTC 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 UTC 2018
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
International immunopharmacology
Shi A,Shi H,Wang Y,Liu X,Cheng Y,Li H,Zhao H,Wang S,Dong L
Mon Jan 01 00:00:00 UTC 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 UTC 2018
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
International immunopharmacology
Jia YN,Lu HP,Peng YL,Zhang BS,Gong XB,Su J,Zhou Y,Pan MH,Xu L
Thu Mar 01 00:00:00 UTC 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 UTC 2018
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L
Tue May 01 00:00:00 UTC 2018
Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signaling.
Toxicology and applied pharmacology
Dong W,Yang B,Wang L,Li B,Guo X,Zhang M,Jiang Z,Fu J,Pi J,Guan D,Zhao R
Tue May 01 00:00:00 UTC 2018
Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signaling.
Toxicology and applied pharmacology
Dong W,Yang B,Wang L,Li B,Guo X,Zhang M,Jiang Z,Fu J,Pi J,Guan D,Zhao R
Tue May 01 00:00:00 UTC 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 UTC 2018
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Neurochemistry international
Zhang J,Tucker LD,Lu Y,Yang L,Wu C,Li Y,Zhang Q
Fri Jun 01 00:00:00 UTC 2018
Knockdown of Nrf2 inhibits angiogenesis by downregulating VEGF expression through PI3K/Akt signaling pathway in cerebral microvascular endothelial cells under hypoxic conditions.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Huang Y,Mao Y,Li H,Shen G,Nan G
Wed Aug 01 00:00:00 UTC 2018
Knockdown of Nrf2 inhibits angiogenesis by downregulating VEGF expression through PI3K/Akt signaling pathway in cerebral microvascular endothelial cells under hypoxic conditions.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Huang Y,Mao Y,Li H,Shen G,Nan G
Wed Aug 01 00:00:00 UTC 2018
Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity.
Neuroscience
Pu D,Zhao Y,Chen J,Sun Y,Lv A,Zhu S,Luo C,Zhao K,Xiao Q
Fri Jun 15 00:00:00 UTC 2018
Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity.
Neuroscience
Pu D,Zhao Y,Chen J,Sun Y,Lv A,Zhu S,Luo C,Zhao K,Xiao Q
Fri Jun 15 00:00:00 UTC 2018
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Journal of applied toxicology : JAT
Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S
Sat Sep 01 00:00:00 UTC 2018
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Journal of applied toxicology : JAT
Li Y,Qian W,Wang D,Meng Y,Wang X,Chen Y,Li X,Xie C,Zhong C,Fu S
Sat Sep 01 00:00:00 UTC 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 UTC 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 UTC 2018
Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats.
Evidence-based complementary and alternative medicine : eCAM
Zhang L,Fan XR,Xie H,He QH,Nie YS,Zhang M,Yan M
Thu Oct 01 00:00:00 UTC 2020
Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats.
Evidence-based complementary and alternative medicine : eCAM
Zhang L,Fan XR,Xie H,He QH,Nie YS,Zhang M,Yan M
Thu Oct 01 00:00:00 UTC 2020
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
International journal of molecular sciences
Tang X,Liu B,Wang X,Yu Q,Fang R
Wed Mar 14 00:00:00 UTC 2018
Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis.
International journal of molecular sciences
Tang X,Liu B,Wang X,Yu Q,Fang R
Wed Mar 14 00:00:00 UTC 2018
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Medicine and science in sports and exercise
Wu C,Yang L,Tucker D,Dong Y,Zhu L,Duan R,Liu TC,Zhang Q
Tue May 01 00:00:00 UTC 2018
Lactobacillus helveticus KLDS1.8701 alleviates d-galactose-induced aging by regulating Nrf-2 and gut microbiota in mice.
Food & function
Li B,Evivie SE,Lu J,Jiao Y,Wang C,Li Z,Liu F,Huo G
Thu Dec 13 00:00:00 UTC 2018
Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells.
Scientific reports
Endo H,Owada S,Inagaki Y,Shida Y,Tatemichi M
Wed Jul 04 00:00:00 UTC 2018
Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells.
Scientific reports
Endo H,Owada S,Inagaki Y,Shida Y,Tatemichi M
Wed Jul 04 00:00:00 UTC 2018
Activation of the Nuclear Erythroid 2-Related Factor 2 Antioxidant Responsive Element (Nrf2-ARE) Signaling Pathway Alleviates Acute Graft-Versus-Host Disease by Reducing Oxidative Stress and Inhibiting Infiltration of Inflammatory Cells in an Allogeneic Stem Cell Transplantation Mouse Model.
Medical science monitor : international medical journal of experimental and clinical research
Yi T,Li X,Wang E,Zhang Y,Fu Y,Li J,Jiang T
Mon Aug 27 00:00:00 UTC 2018
Activation of the Nuclear Erythroid 2-Related Factor 2 Antioxidant Responsive Element (Nrf2-ARE) Signaling Pathway Alleviates Acute Graft-Versus-Host Disease by Reducing Oxidative Stress and Inhibiting Infiltration of Inflammatory Cells in an Allogeneic Stem Cell Transplantation Mouse Model.
Medical science monitor : international medical journal of experimental and clinical research
Yi T,Li X,Wang E,Zhang Y,Fu Y,Li J,Jiang T
Mon Aug 27 00:00:00 UTC 2018
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Redox biology
Zhao L,Tao X,Qi Y,Xu L,Yin L,Peng J
Fri Jun 01 00:00:00 UTC 2018
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Redox biology
Zhao L,Tao X,Qi Y,Xu L,Yin L,Peng J
Fri Jun 01 00:00:00 UTC 2018
Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu YR,Ma H,Zou ZY,He K,Xiao YB,Wang Y,Feng M,Ye XL,Li XG
Sun Jan 01 00:00:00 UTC 2017
Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu YR,Ma H,Zou ZY,He K,Xiao YB,Wang Y,Feng M,Ye XL,Li XG
Sun Jan 01 00:00:00 UTC 2017
Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice.
Oxidative medicine and cellular longevity
Wu H,Zhang G,Huang L,Pang H,Zhang N,Chen Y,Wang G
Mon Mar 19 00:00:00 UTC 2018
Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice.
Oxidative medicine and cellular longevity
Wu H,Zhang G,Huang L,Pang H,Zhang N,Chen Y,Wang G
Mon Mar 19 00:00:00 UTC 2018
Apigenin exhibits protective effects in a mouse model of d-galactose-induced aging via activating the Nrf2 pathway.
Food & function
Sang Y,Zhang F,Wang H,Yao J,Chen R,Zhou Z,Yang K,Xie Y,Wan T,Ding H
Wed Jun 21 00:00:00 UTC 2017
Apigenin exhibits protective effects in a mouse model of d-galactose-induced aging via activating the Nrf2 pathway.
Food & function
Sang Y,Zhang F,Wang H,Yao J,Chen R,Zhou Z,Yang K,Xie Y,Wan T,Ding H
Wed Jun 21 00:00:00 UTC 2017
Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen S,Li J,You H,Wu Z,Wu Y,Zhao Y,Zhu Y,Guo Q,Li X,Li R,Ma P,Yang X,Chen M
Sun Jan 01 00:00:00 UTC 2017
Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Shen S,Li J,You H,Wu Z,Wu Y,Zhao Y,Zhu Y,Guo Q,Li X,Li R,Ma P,Yang X,Chen M
Sun Jan 01 00:00:00 UTC 2017
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
World journal of gastroenterology
Sang L,Wang XM,Xu DY,Sang LX,Han Y,Jiang LY
Thu Dec 21 00:00:00 UTC 2017
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
World journal of gastroenterology
Sang L,Wang XM,Xu DY,Sang LX,Han Y,Jiang LY
Thu Dec 21 00:00:00 UTC 2017
Reduction of oxidative damages induced by titanium dioxide nanoparticles correlates with induction of the Nrf2 pathway by GSPE supplementation in mice.
Chemico-biological interactions
Niu L,Shao M,Liu Y,Hu J,Li R,Xie H,Zhou L,Shi L,Zhang R,Niu Y
Mon Sep 25 00:00:00 UTC 2017
Reduction of oxidative damages induced by titanium dioxide nanoparticles correlates with induction of the Nrf2 pathway by GSPE supplementation in mice.
Chemico-biological interactions
Niu L,Shao M,Liu Y,Hu J,Li R,Xie H,Zhou L,Shi L,Zhang R,Niu Y
Mon Sep 25 00:00:00 UTC 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 UTC 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 UTC 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 UTC 2017
The electrophilic character of quinones is essential for the suppression of Bach1.
Toxicology
Su C,Liu Z,Wang Y,Wang Y,Song E,Song Y
Sat Jul 15 00:00:00 UTC 2017
Procyanidin B2 ameliorates carrageenan-induced chronic nonbacterial prostatitis in rats via anti-inflammatory and activation of the Nrf2 pathway.
Biochemical and biophysical research communications
Wang W,Chen R,Wang J
Sat Nov 04 00:00:00 UTC 2017
Procyanidin B2 ameliorates carrageenan-induced chronic nonbacterial prostatitis in rats via anti-inflammatory and activation of the Nrf2 pathway.
Biochemical and biophysical research communications
Wang W,Chen R,Wang J
Sat Nov 04 00:00:00 UTC 2017
Naringenin Ameliorates Behavioral Dysfunction and Neurological Deficits in a d-Galactose-Induced Aging Mouse Model Through Activation of PI3K/Akt/Nrf2 Pathway.
Rejuvenation research
Zhang Y,Liu B,Chen X,Zhang N,Li G,Zhang LH,Tan LY
Fri Dec 01 00:00:00 UTC 2017
Naringenin Ameliorates Behavioral Dysfunction and Neurological Deficits in a d-Galactose-Induced Aging Mouse Model Through Activation of PI3K/Akt/Nrf2 Pathway.
Rejuvenation research
Zhang Y,Liu B,Chen X,Zhang N,Li G,Zhang LH,Tan LY
Fri Dec 01 00:00:00 UTC 2017
Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes.
Experimental biology and medicine (Maywood, N.J.)
Yuan X,Huang H,Huang Y,Wang J,Yan J,Ding L,Zhang C,Zhang L
Mon May 01 00:00:00 UTC 2017
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 UTC 2016
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 UTC 2016
Myricetin alleviates cuprizone-induced behavioral dysfunction and demyelination in mice by Nrf2 pathway.
Food & function
Zhang Q,Li Z,Wu S,Li X,Sang Y,Li J,Niu Y,Ding H
Wed Oct 12 00:00:00 UTC 2016
Myricetin alleviates cuprizone-induced behavioral dysfunction and demyelination in mice by Nrf2 pathway.
Food & function
Zhang Q,Li Z,Wu S,Li X,Sang Y,Li J,Niu Y,Ding H
Wed Oct 12 00:00:00 UTC 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 UTC 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 UTC 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 UTC 2016
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Toxicology
Su C,Shi Q,Song X,Fu J,Liu Z,Wang Y,Wang Y,Xia X,Song E,Song Y
Fri Jul 01 00:00:00 UTC 2016
Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.
Toxicology
Su C,Shi Q,Song X,Fu J,Liu Z,Wang Y,Wang Y,Xia X,Song E,Song Y
Fri Jul 01 00:00:00 UTC 2016
Rice protein suppresses ROS generation and stimulates antioxidant gene expression via Nrf2 activation in adult rats.
Gene
Li H,He H,Wang Z,Cai J,Sun B,Wu Q,Zhang Y,Zhou G,Yang L
Sun Jul 10 00:00:00 UTC 2016
Rice protein suppresses ROS generation and stimulates antioxidant gene expression via Nrf2 activation in adult rats.
Gene
Li H,He H,Wang Z,Cai J,Sun B,Wu Q,Zhang Y,Zhou G,Yang L
Sun Jul 10 00:00:00 UTC 2016
Keap1 hypomorphism protects against ischemic and obstructive kidney disease.
Scientific reports
Tan RJ,Chartoumpekis DV,Rush BM,Zhou D,Fu H,Kensler TW,Liu Y
Wed Nov 02 00:00:00 UTC 2016
Keap1 hypomorphism protects against ischemic and obstructive kidney disease.
Scientific reports
Tan RJ,Chartoumpekis DV,Rush BM,Zhou D,Fu H,Kensler TW,Liu Y
Wed Nov 02 00:00:00 UTC 2016
Systematic revelation of the protective effect and mechanism of Cordycep sinensis on diethylnitrosamine-induced rat hepatocellular carcinoma with proteomics.
Oncotarget
Wang PW,Hung YC,Li WT,Yeh CT,Pan TL
Tue Sep 13 00:00:00 UTC 2016
Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice.
Toxicology research
Zhu Y,Li J,Wu Z,Lu Y,You H,Li R,Li B,Yang X,Duan L
Fri Jan 01 00:00:00 UTC 2016
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Scientific reports
Zheng ZG,Xu H,Suo SS,Xu XL,Ni MW,Gu LH,Chen W,Wang LY,Zhao Y,Tian B,Hua YJ
Thu May 19 00:00:00 UTC 2016
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Scientific reports
Zheng ZG,Xu H,Suo SS,Xu XL,Ni MW,Gu LH,Chen W,Wang LY,Zhao Y,Tian B,Hua YJ
Thu May 19 00:00:00 UTC 2016
Reduction of DNA damage induced by titanium dioxide nanoparticles through Nrf2 in vitro and in vivo.
Journal of hazardous materials
Shi Z,Niu Y,Wang Q,Shi L,Guo H,Liu Y,Zhu Y,Liu S,Liu C,Chen X,Zhang R
Sun Nov 15 00:00:00 UTC 2015
Reduction of DNA damage induced by titanium dioxide nanoparticles through Nrf2 in vitro and in vivo.
Journal of hazardous materials
Shi Z,Niu Y,Wang Q,Shi L,Guo H,Liu Y,Zhu Y,Liu S,Liu C,Chen X,Zhang R
Sun Nov 15 00:00:00 UTC 2015
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 UTC 2015
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 UTC 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 UTC 2015
Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chemical research in toxicology
Su C,Zhang P,Song X,Shi Q,Fu J,Xia X,Bai H,Hu L,Xu D,Song E,Song Y
Mon Apr 20 00:00:00 UTC 2015
Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary fibrosis in rat by activating Nrf2 signaling.
International journal of clinical and experimental pathology
Ni S,Wang D,Qiu X,Pang L,Song Z,Guo K
Wed Dec 14 00:00:00 UTC 2016
Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary fibrosis in rat by activating Nrf2 signaling.
International journal of clinical and experimental pathology
Ni S,Wang D,Qiu X,Pang L,Song Z,Guo K
Wed Dec 14 00:00:00 UTC 2016
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 UTC 2014
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Toxicology and applied pharmacology
Xu D,Hu L,Su C,Xia X,Zhang P,Fu J,Wang W,Xu D,Du H,Hu Q,Song E,Song Y
Wed Oct 15 00:00:00 UTC 2014
The decrease of NAD(P)H:quinone oxidoreductase 1 activity and increase of ROS production by NADPH oxidases are early biomarkers in doxorubicin cardiotoxicity.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Lagoa R,Gañán C,López-Sánchez C,García-Martínez V,Gutierrez-Merino C
Sat Mar 01 00:00:00 UTC 2014
The decrease of NAD(P)H:quinone oxidoreductase 1 activity and increase of ROS production by NADPH oxidases are early biomarkers in doxorubicin cardiotoxicity.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Lagoa R,Gañán C,López-Sánchez C,García-Martínez V,Gutierrez-Merino C
Sat Mar 01 00:00:00 UTC 2014
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 UTC 2015
Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.
International journal of clinical and experimental pathology
Zhao F,Li K,Zhao L,Liu J,Suo Q,Zhao J,Wang H,Zhao S
Tue May 26 00:00:00 UTC 2015
Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus.
PloS one
Sugiyama K,Ebinuma H,Nakamoto N,Sakasegawa N,Murakami Y,Chu PS,Usui S,Ishibashi Y,Wakayama Y,Taniki N,Murata H,Saito Y,Fukasawa M,Saito K,Yamagishi Y,Wakita T,Takaku H,Hibi T,Saito H,Kanai T
Mon Jun 29 00:00:00 UTC 2015
Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus.
PloS one
Sugiyama K,Ebinuma H,Nakamoto N,Sakasegawa N,Murakami Y,Chu PS,Usui S,Ishibashi Y,Wakayama Y,Taniki N,Murata H,Saito Y,Fukasawa M,Saito K,Yamagishi Y,Wakita T,Takaku H,Hibi T,Saito H,Kanai T
Mon Jun 29 00:00:00 UTC 2015
Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis.
PloS one
Endo H,Niioka M,Kobayashi N,Tanaka M,Watanabe T
Mon Dec 23 00:00:00 UTC 2013
Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis.
PloS one
Endo H,Niioka M,Kobayashi N,Tanaka M,Watanabe T
Mon Dec 23 00:00:00 UTC 2013
Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis.
PloS one
Endo H,Niioka M,Kobayashi N,Tanaka M,Watanabe T
Mon Dec 23 00:00:00 UTC 2013
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Cell reports
Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D
Thu May 30 00:00:00 UTC 2013
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Cell reports
Wu H,Xiao Y,Zhang S,Ji S,Wei L,Fan F,Geng J,Tian J,Sun X,Qin F,Jin C,Lin J,Yin ZY,Zhang T,Luo L,Li Y,Song S,Lin SC,Deng X,Camargo F,Avruch J,Chen L,Zhou D
Thu May 30 00:00:00 UTC 2013
Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade.
EMBO reports
Kwon J,Han E,Bui CB,Shin W,Lee J,Lee S,Choi YB,Lee AH,Lee KH,Park C,Obin MS,Park SK,Seo YJ,Oh GT,Lee HW,Shin J
Wed Feb 01 00:00:00 UTC 2012
Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade.
EMBO reports
Kwon J,Han E,Bui CB,Shin W,Lee J,Lee S,Choi YB,Lee AH,Lee KH,Park C,Obin MS,Park SK,Seo YJ,Oh GT,Lee HW,Shin J
Wed Feb 01 00:00:00 UTC 2012
Persistent expression of Nqo1 by p62-mediated Nrf2 activation facilitates p53-dependent mitotic catastrophe.
Biochemical and biophysical research communications
Bui CB,Shin J
Fri Aug 26 00:00:00 UTC 2011
Persistent expression of Nqo1 by p62-mediated Nrf2 activation facilitates p53-dependent mitotic catastrophe.
Biochemical and biophysical research communications
Bui CB,Shin J
Fri Aug 26 00:00:00 UTC 2011
Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane.
Molecular and cellular neurosciences
Samhan-Arias AK,Garcia-Bereguiain MA,Martin-Romero FJ,Gutierrez-Merino C
Thu Jan 01 00:00:00 UTC 2009
Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane.
Molecular and cellular neurosciences
Samhan-Arias AK,Garcia-Bereguiain MA,Martin-Romero FJ,Gutierrez-Merino C
Thu Jan 01 00:00:00 UTC 2009
Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane.
Molecular and cellular neurosciences
Samhan-Arias AK,Garcia-Bereguiain MA,Martin-Romero FJ,Gutierrez-Merino C
Thu Jan 01 00:00:00 UTC 2009
Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane.
Molecular and cellular neurosciences
Samhan-Arias AK,Garcia-Bereguiain MA,Martin-Romero FJ,Gutierrez-Merino C
Thu Jan 01 00:00:00 UTC 2009
