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          • Primary Antibodies ›
          • NR1D2 Antibodies

          Invitrogen

          NR1D2 Polyclonal Antibody

          View all (19) NR1D2 antibodies

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          Cite NR1D2 Polyclonal Antibody

          • Antibody Testing Data (2)
          NR1D2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          NR1D2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 2

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          NR1D2 Antibody (PA5-32948) in IHC (P)

          Immunohistochemistry analysis of NR1D2 in human thyroid. Samples were incubated with NR1D2 polyclonal antibody (Product # PA5-32948). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NR1D2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NR1D2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-32948

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          10 µg/mL
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Bat, Bovine, Dog, Chicken, Horse, Human, Mouse, Non-human primate, Rabbit, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic 16 amino acid peptide from internal region of human NR1D2.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.1% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2550409

          Product Specific Information

          Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Panda, Horse, Rabbit, Turkey, Chicken (100%); Elephant, Platypus (94%); Opossum, Xenopus (81%).

          For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

          Target Information

          This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: EAR-1R; EAR4; HZF2; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta variant 2; Nuclear receptor subfamily 1 group D member 2; nuclear receptor subfamily 1, group D, member 2; Orphan nuclear hormone receptor BD73; orphan nuclear receptor HZF-2; Orphan nuclear receptor RVR; orphan receptor; Rev-erb alpha-related receptor; Rev-erb beta; Rev-erb-beta; Rev-erb-Beta2; Rev-erba beta; rev-erba-alpha-related receptor; Rev-ErbA-beta; Rev-erbabeta; RVR; V-erbA-related protein 1-related

          View more View less

          Gene Aliases: BD73; EAR-1R; HZF-2; NR1D2; Rev-erb; REV-ERBB; RVR

          View more View less

          UniProt ID: (Human) Q14995, (Mouse) Q60674, (Rat) Q63504

          View more View less

          Entrez Gene ID: (Rabbit) 100349421, (Human) 9975, (Dog) 485643, (Chicken) 396125, (Mouse) 353187, (Rat) 259241

          View more View less

          Function(s)
          core promoter sequence-specific DNA binding steroid hormone receptor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding protein binding zinc ion binding DNA binding transcription factor activity, sequence-specific DNA binding thyroid hormone receptor activity sequence-specific DNA binding metal ion binding
          Process(es)
          transcription, DNA-templated regulation of transcription, DNA-templated regulation of lipid metabolic process regulation of circadian rhythm steroid hormone mediated signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated rhythmic process regulation of inflammatory response lipid homeostasis regulation of energy homeostasis regulation of skeletal muscle cell differentiation transcription initiation from RNA polymerase II promoter intracellular receptor signaling pathway
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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