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Proteintech
NR2C1 Polyclonal Antibody
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Product Details
13658-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NR2C1 Fusion Protein Ag4554 (118-467 aa encoded by BC040141)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DKASGRHYG AVTCEGCKGF FKRSIRKNLV YSCRGSKDCI INKHHRNRCQ YCRLQRCIAF GMKQDSVQCE RKPIEVSREK SSNCAASTEK IYIRKDLRSP LTATPTFVTD SESTRSTGLL DSGMFMNIHP SGVKTESAVL MTSDKAESCQ GDLSTLANVV TSLANLGKTK DLSQNSNEMS MIESLSNDDT SLCEFQEMQT NGDVSRAFDT LAKALNPGES TACQSSVAGM EGSVHLITGD SSINYTEKEG PLLSDSHVAF RLTMPSPMPE YLNVHYIGES ASRLLFLSMH WALSIPSFQA LGQENSISLV KAYWNELFTL GLAQCWQVMN VATILATFVN CLHNSLQQAE G (118-467 aa encoded by BC040141)
Target Information
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 80-3 cNDA; early embryonic nuclear receptor; mTR2; nr2c1; Nuclear receptor subfamily 2 group C member 1; nuclear receptor subfamily 2, group C isoform; nuclear receptor subfamily 2, group C, member 1; nuclear receptor subfamily 2, group H, member 1; Orphan nuclear receptor TR2; orphan receptor, TR2-11; pregnancy specific beta-1-glycoprotein 4; Testicular receptor 2; TR2 nuclear hormone receptor
Gene Aliases: 4831444H07Rik; 80.3; Eenr; NR2C1; Psg4; TR2; TR2-11
UniProt ID: (Human) P13056, (Mouse) Q505F1, (Rat) Q8VIJ4
Entrez Gene ID: (Human) 7181, (Mouse) 22025, (Rat) 252924
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
steroid hormone receptor activity
receptor activity
protein binding
zinc ion binding
protein homodimerization activity
histone deacetylase binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
steroid hormone mediated signaling pathway
positive regulation of retinoic acid receptor signaling pathway
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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