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Product Details
67489-1-IG
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2E4C10
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Nuclear hormone receptor TR4; Nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; nuclear receptor subfamily 2, group H, member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; orphan receptor TR4; orphan receptor, TR4; testicular nuclear receptor 4; Testicular receptor 4; TR2R1; TR4 orphan receptor; TR4-NS orphan receptor
Gene Aliases: mKIAA4145; Mtr2r1; NR2C2; TAK1; TR4
UniProt ID: (Human) P49116, (Rat) P55094, (Mouse) P49117
Entrez Gene ID: (Human) 7182, (Rat) 50659, (Mouse) 22026
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
spermatogenesis
nervous system development
cerebellum development
cell differentiation
p38MAPK cascade
positive regulation of embryonic development
steroid hormone mediated signaling pathway
positive regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of behavior
meiotic cell cycle
mitophagy in response to mitochondrial depolarization
transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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