Proteintech

NRD1 Polyclonal Antibody

NRD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 6

NRD1 Antibody (15630-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using (Product # 15630-1-AP) (NRD1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Product Details

15630-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NRD1 Fusion Protein Ag7923 (801-1150 aa encoded by BC008775)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: YFNILIKPE TLAKDVRLLI LEYARWSMID KYQALMDGLS LESLLSFVKE FKSQLFVEGL VQGNVTSTES MDFLKYVVDK LNFKPLEQEM PVQFQVVELP SGHHLCKVKA LNKGDANSEV TVYYQSGTRS LREYTLMELL VMHMEEPCFD FLRTKQTLGY HVYPTCRNTS GILGFSVTVG TQATKYNSEV VDKKIEEFLS SFEEKIENLT EEAFNTQVTA LIKLKECEDT HLGEEVDRNW NEVVTQQYLF DRLAHEIEAL KSFSKSDLVN WFKAHRGPGS KMLSVHVVGY GKYELEEDGT PSSEDSNSSC EVMQLTYLPT SPLLADCIIP ITDIRAFTTT LNLLPYHKIV K (801-1150 aa encoded by BC008775)

Target Information

Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Serum Nardilysin as a Prognostic Biomarker in Pancreatic Ductal Adenocarcinoma.

Journal of clinical medicine

Xu Y,Xiong Q,Yang Y,Weng N,Li J,Liu J,Yang X,Zeng Z,Zhang Z,Zhu Q

Mon May 30 00:00:00 UTC 2022

Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes.

Journal of immunology (Baltimore, Md. : 1950)

Radichev IA,Maneva-Radicheva LV,Amatya C,Salehi M,Parker C,Ellefson J,Burn P,Savinov AY

Mon Feb 15 00:00:00 UTC 2016

Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.

Diabetes

Radichev IA,Maneva-Radicheva LV,Amatya C,Parker C,Ellefson J,Wasserfall C,Atkinson M,Burn P,Savinov AY

Wed Oct 01 00:00:00 UTC 2014

Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.

Diabetes

Radichev IA,Maneva-Radicheva LV,Amatya C,Parker C,Ellefson J,Wasserfall C,Atkinson M,Burn P,Savinov AY

Wed Oct 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: N-arginine dibasic convertase; Nardilysin; nardilysin (N-arginine dibasic convertase); Nardilysin convertase; NRD convertase

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Gene Aliases: 2600011I06Rik; AI875733; hNRD1; hNRD2; NRD-C; NRD1; NRDC

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UniProt ID: (Human) O43847, (Mouse) Q8BHG1

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Entrez Gene ID: (Human) 4898, (Mouse) 230598

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Function(s)

metalloendopeptidase activity protein binding zinc ion binding epidermal growth factor binding catalytic activity peptidase activity metallopeptidase activity hydrolase activity metal ion binding

Process(es)

proteolysis positive regulation of membrane protein ectodomain proteolysis regulation of endopeptidase activity neuromuscular junction development cell proliferation cell migration protein processing

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NRD1 Polyclonal Antibody

NRD1 Antibody (15630-1-AP) in IHC (P)

Product Details

15630-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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