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Invitrogen
NRXN1 Polyclonal Antibody
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NRXN1 Antibody (PA5-79764) in WB
Western blot analysis of NRXN1 using NRXN1 Polyclonal Antibody (Product # PA5-79764). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel)/90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human U87 whole cell lysates. Lane 2: human U251 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membra... View More
Product Details
PA5-79764
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746879
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human U87 whole cell, human U251 whole cell. Flow: SH-SY5Y cell.
Target Information
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp313P2036; FLJ35941; Neurexin 1alpha; neurexin I; Neurexin I-alpha; Neurexin I-beta; Neurexin-1; Neurexin-1-alpha; Neurexin-1-beta
Gene Aliases: Hs.22998; KIAA0578; NRXN1; PTHSL2; SCZD17
UniProt ID: (Human) Q9ULB1
Entrez Gene ID: (Human) 9378
neuron cell-cell adhesion
chemical synaptic transmission
neurotransmitter secretion
axon guidance
synapse assembly
learning
adult behavior
social behavior
vocal learning
neuromuscular process controlling balance
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
prepulse inhibition
regulation of insulin secretion involved in cellular response to glucose stimulus
vocalization behavior
positive regulation of synapse maturation
postsynaptic membrane assembly
gephyrin clustering involved in postsynaptic density assembly
neuroligin clustering involved in postsynaptic membrane assembly
postsynaptic density protein 95 clustering
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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