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Product Details
PA5-87525
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 251-400 of human NSF (NP_0061692)
Conjugate
Form
Liquid
Concentration
1.37 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804224
Product Specific Information
Immunogen sequence: KHVKGILLYG PPGCGKTLLA RQIGKMLNAR EPKVVNGPEI LNKYVGESEA NIRKLFADAE EEQRRLGANS GLHIIIFDEI DAICKQRGSM AGSTGVHDTV VNQLLSKIDG VEQLNNILVI GMTNRPDLID EALLRPGRLE VKMEIGLPDE
Positive Samples: Mouse brain, Rat brain; Cellular Location: Cytoplasm
Target Information
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: N-ethylmaleimide sensitive factor; N-ethylmaleimide sensitive fusion protein; N-ethylmaleimide-sensitive factor; N-ethylmaleimide-sensitive factor-like protein; N-ethylmaleimide-sensitive fusion protein; NEM-sensitive fusion protein; Protein SKD2; Suppressor of K(+) transport growth defect 2; Vesicle-fusing ATPase; Vesicular-fusion protein NSF
Gene Aliases: AI316878; AU020090; AU067812; Erg1; NSF; SKD2
UniProt ID: (Human) P46459, (Mouse) P46460, (Rat) Q9QUL6
Entrez Gene ID: (Human) 4905, (Mouse) 18195, (Rat) 60355
protein binding
ATP binding
ATPase activity
syntaxin-1 binding
Rab GTPase binding
protein kinase binding
PDZ domain binding
protein complex binding
ATPase activity, coupled
metal ion binding
nucleotide binding
protein C-terminus binding
hydrolase activity
syntaxin binding
D1 dopamine receptor binding
ATP-dependent protein binding
positive regulation of receptor recycling
potassium ion transport
intracellular protein transport
exocytosis
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
intra-Golgi vesicle-mediated transport
vesicle-mediated transport
regulation of exocytosis
Golgi to plasma membrane protein transport
plasma membrane fusion
positive regulation of protein catabolic process
COPII vesicle coating
Golgi vesicle docking
transport
metabolic process
protein transport
vesicle fusion
neurotransmitter secretion
membrane fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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