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Invitrogen
NSUN6 Polyclonal Antibody
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Product Details
PA5-61119
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NSUN6. Recombinant protein control fragment (Product #RP-97123).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2644825
Product Specific Information
Immunogen sequence: VLLIPVIGPR KNIKKQQCEA IVGAQCGNAV LRGAHVYAPG IVSASQFMKA GDVISVYSDI KGKCKKGAKE FDGTKVFLGN GISELSRKEI FSG
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.
Target Information
NSun6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSun6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARL5B antisense RNA 1; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family member 6; NOL1/NOP2/Sun domain family, member 6; NOP2/Sun domain family, member 6; nucleolar protein (NOL1/NOP2/sun) and PUA domains 1; tRNA (cytosine(72)-C(5))-methyltransferase NSUN6
Gene Aliases: 4933414E04Rik; ARL5B-AS1; NOPD1; NSUN6
UniProt ID: (Human) Q8TEA1
Entrez Gene ID: (Human) 221078
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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