Invitrogen

NT5M Polyclonal Antibody

View all (5) NT5M antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-118920

Applications
Tested Dilution
Publications

Western Blot (WB)

0.5-2 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

5-20 µg/mL
-

Immunocytochemistry (ICC/IF)

5-20 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein 5'-Nucleotidase, Mitochondrial. The antigen corresponds to amino acid range 38-228 of the target protein.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2903420

Target Information

Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 5' nucleotidase, mitochondrial; 5'(3')-deoxyribonucleotidase, mitochondrial; 5',3'-deoxyribonucleotidase, mitochondrial; 5',3'-nucleotidase, mitochondrial; 5(3)-deoxyribonucleotidase; Deoxy-5'-nucleotidase 2; dNT-2; mitochondrial 5' nucleotidase

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Gene Aliases: 2010013E09Rik; AI846937; dNT-2; DNT2; mdN; NT5M

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UniProt ID: (Human) Q9NPB1, (Mouse) Q8VCE6

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Entrez Gene ID: (Human) 56953, (Mouse) 103850

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Function(s)
nucleotide binding nucleotidase activity 5'-nucleotidase activity metal ion binding protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity phosphohistidine phosphatase activity inositol bisphosphate phosphatase activity hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity inositol-1,3,4-trisphosphate 4-phosphatase activity NADP phosphatase activity transmembrane receptor protein phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity inositol-4,5-bisphosphate 5-phosphatase activity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity phosphatidylinositol-4-phosphate phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity inositol phosphate phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity inositol-3,4-bisphosphate 4-phosphatase activity inositol-1,3,4-trisphosphate 1-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity IDP phosphatase activity
Process(es)
DNA replication pyrimidine deoxyribonucleotide catabolic process dephosphorylation dUMP catabolic process pyrimidine nucleoside catabolic process nucleotide metabolic process deoxyribonucleotide catabolic process
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