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Proteintech
NTN1 Polyclonal Antibody
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Product Details
20235-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
173 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Netrin-G1 ligand (NGL1) is a transmembrane protein containing leucine-rich repeat (LRR) and immunoglobulin (Ig) domains that specifically interact with netrin-G1 through its LRR region. Whereas netrin-G1 is expressed highly in mouse thalamic axons, NGL1 is most abundant in the striatum and the cerebral cortex. NGL1 is implicated in facilitating axonal growth of the vertebrate CNS. Membrane-bound netrin-G1 acts as an axonal receptor, whereas the LRR-containing transmembrane protein NGL1 acts as a ligand in promoting the growth of thalamic axons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Epididymis tissue protein Li 131P; HGNC:8029; netrin 1, mouse, homolog of; Netrin-1; Netrin1
Gene Aliases: AI561871; BC019633; Netrin-1; NTN1; NTN1L
UniProt ID: (Human) O95631, (Mouse) O09118
Entrez Gene ID: (Human) 9423, (Mouse) 18208, (Rat) 114523
neuron migration
apoptotic process
axonogenesis
axon guidance
positive regulation of cell proliferation
single organismal cell-cell adhesion
regulation of cell migration
negative regulation of axon extension
mammary gland development
anterior/posterior axon guidance
establishment of nucleus localization
inner ear morphogenesis
positive regulation of axon extension
mammary gland duct morphogenesis
substrate-dependent cell migration, cell extension
Ras protein signal transduction
Cdc42 protein signal transduction
positive regulation of cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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