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Bethyl Laboratories
NUCKS Polyclonal Antibody
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Product Details
IHC-00303
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1 and 50 of human nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Horse, Guinea pig_10141, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Naked mole rat
Target Information
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: JC7; nuclear casein kinase and cyclin-dependent kinase substrate 1; Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; nuclear ubiquitous casein and cyclin-dependent kinases substrate; nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate; nuclear, casein kinase and cyclin-dependent kinase substrate; P1; potential LAG1 interactor
Gene Aliases: 2700010L10Rik; 8430423A01Rik; AI647518; C78391; JC7; NUCKS; NUCKS1
UniProt ID: (Human) Q9H1E3, (Mouse) Q80XU3
Entrez Gene ID: (Human) 64710, (Mouse) 98415
biological_process
double-strand break repair via homologous recombination
cellular glucose homeostasis
regulation of DNA replication
chromatin organization
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
release from viral latency
replication fork processing
gene conversion
interstrand cross-link repair
positive regulation by host of viral transcription
positive regulation by host of viral genome replication
modulation by host of viral molecular function
positive regulation of transcription from RNA polymerase II promoter
regulation of insulin receptor signaling pathway
positive regulation of insulin receptor signaling pathway
regulation of DNA strand elongation
cellular response to X-ray
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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