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Product Details
17508-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NUDT10 Fusion Protein Ag11711 (1-164 aa encoded by BC050700)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKCKPNQTR TYDPEGFKKR AACLCFRSER EDEVLLVSSS RYPDRWIVPG GGMEPEEEPG GAAVREVYEE AGVKGKLGRL LGVFEQNQDP EHRTYVYVLT VTELLEDWED SVSIGRKREW FKVEDAIKVL QCHKPVHAEY LEKLKLGGSP TNGNSMAPSS PDSDP (1-164 aa encoded by BC050700)
Target Information
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming); Diphosphoinositol polyphosphate phosphohydrolase 3-alpha; Diphosphoinositol polyphosphate phosphohydrolase 3-beta; DIPP-3-alpha; DIPP-3-beta; DIPP3 alpha; DIPP3-alpha; hAps2; hDIPP3alpha; Nucleoside diphosphate-linked moiety X motif 10; Nucleoside diphosphate-linked moiety X motif 11; nudix (nucleoside diphosphate linked moiety X)-type motif 10; Nudix motif 10; Nudix motif 11
Gene Aliases: AI853080; APS2; DIPP3-alpha; DIPP3A; Dipp3b; MNCb-1696; NUDT10; Nudt11; RGD1564763
UniProt ID: (Human) Q8NFP7, (Mouse) P0C027
Entrez Gene ID: (Human) 170685, (Rat) 367747, (Mouse) 102954
protein binding
diphosphoinositol-polyphosphate diphosphatase activity
metal ion binding
inositol diphosphate tetrakisphosphate diphosphatase activity
inositol bisdiphosphate tetrakisphosphate diphosphatase activity
inositol diphosphate pentakisphosphate diphosphatase activity
inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity
inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity
inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
hydrolase activity
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