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Proteintech
NUP133 Polyclonal Antibody
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Product Details
12405-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NUP133 Fusion Protein Ag3100 (857-1156 aa encoded by BC020107)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LWAASLAEK YCDFDILVQM CEQTDNQSRL QRYMTQFADQ NFSDFLFRWY LEKGKRGKLL SQPISQHGQL ANFLQAHEHL SWLHEINSQE LEKAHATLLG LANMETRYFA KKKTLLGLSK LAALASDFSE DMLQEKIEEM AEQERFLLHQ ETLPEQLLAE KQLNLSAMPV LTAPQLIGLY ICEENRRANE YDFKKALDLL EYIDEEEDIN INDLKLEILC KALQRDNWSS SDGKDDPIEV SKDSIFVKIL QKLLKDGIQL SEYLPEVKDL LQADQLGSLK SNPYFEFVLK ANYEYYVQGQ I (857-1156 aa encoded by BC020107)
Target Information
Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 133 kDa nucleoporin; Nuclear pore complex protein Nup133; nucleoporin 133; nucleoporin 133kD; nucleoporin 133kDa; Nucleoporin Nup133
Gene Aliases: hNUP133; mermaid; NUP133
UniProt ID: (Human) Q8WUM0, (Mouse) Q8R0G9
Entrez Gene ID: (Human) 55746, (Mouse) 234865, (Rat) 292085
mRNA export from nucleus
transport
nuclear pore organization
protein transport
paraxial mesoderm development
mRNA transport
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
chromatin organization
regulation of transcription, DNA-templated
tRNA export from nucleus
protein import into nucleus
sister chromatid cohesion
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
neural tube development
neurogenesis
gene silencing by RNA
nuclear pore distribution
somite development
intracellular transport of virus
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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