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Invitrogen
NUP50 Polyclonal Antibody
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NUP50 Antibody (PA5-97215) in IHC (P)
Immunohistochemistry analysis of NUP50 in paraffin-embedded rat testis. Samples were incubated with NUP50 Polyclonal antibody (Product # PA5-97215) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
PA5-97215
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 340-468 of human NUP50 (NP_0091032)
Conjugate
Form
Liquid
Concentration
1.67 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2809017
Product Specific Information
Immunogen sequence: ENDEPPKVVV TEVKEEDAFY SKKCKLFYKK DNEFKEKGIG TLHLKPTANQ KTQLLVRADT NLGNILLNVL IPPNMPCTRT GKNNVLIVCV PNPPIDEKNA TMPVTMLIRV KTSEDADELH KILLEKKDA
Positive Samples: HeLa, Jurkat, Mouse thymus; Cellular Location: Nucleoplasmic side, Nucleus, Nucleus membrane, Peripheral membrane protein, nuclear pore complex
Target Information
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 50 kDa nucleoporin; CTA-268H5.7; DKFZP564A043; MGC39961; nuclear pore associated protein 60 kDa; Nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50 kDa; nucleoporin 50kD; nucleoporin 50kDa; Nucleoporin Nup50; nucleoprotein 50; Nucleoprotein 50kD; NUP50 protein; OTTHUMP00000199530
Gene Aliases: 1700030K07Rik; AI413123; NPAP60; NPAP60L; NUP50; PRO1146; Rtp60
UniProt ID: (Human) Q9UKX7, (Rat) O08587, (Mouse) Q9JIH2
Entrez Gene ID: (Human) 10762, (Rat) 25497, (Mouse) 18141
neural tube formation
nucleocytoplasmic transport
protein transport
intracellular transport
mRNA transport
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
intracellular transport of virus
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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