Invitrogen

NUP62 Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-21435

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Nucleoporin p62. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol, 1% BSA

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11153933

Product Specific Information

Recommended positive controls: A431, H1299, Neuro 2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12, PC-12, Rat2.

Predicted reactivity: Mouse (95%), Rat (95%), Xenopus laevis (89%), Rhesus Monkey (99%), Bovine (96%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

SDS3 is a subunit of the histone deacetylase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 62 kDa nucleoporin; DKFZp547L134; FLJ20822; FLJ43869; MGC841; nuclear pore complex 1; nuclear pore glycoprotein 62; Nuclear pore glycoprotein p62; nucleoporin 62kD; nucleoporin 62kDa; Nucleoporin Nup62; nucleoporin p62

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Gene Aliases: AA589433; AI426861; AI790512; AU045898; D7Ertd649e; IBSN; Np62; NUP62; Nupc1; p62; SNDI

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UniProt ID: (Human) P37198, (Rat) P17955, (Mouse) Q63850

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Entrez Gene ID: (Human) 23636, (Rat) 65274, (Mouse) 18226

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Function(s)
chromatin binding nucleocytoplasmic transporter activity protein binding phospholipid binding structural constituent of nuclear pore kinesin binding receptor signaling complex scaffold activity Hsp70 protein binding SH2 domain binding ubiquitin binding thyroid hormone receptor binding PTB domain binding Hsp90 protein binding
Process(es)
transcription, DNA-templated RNA export from nucleus mRNA export from nucleus tRNA export from nucleus protein import into nucleus mitotic nuclear division mitotic nuclear envelope disassembly cell surface receptor signaling pathway spermatogenesis cell aging cell death negative regulation of cell proliferation hormone-mediated signaling pathway regulation of signal transduction regulation of glucose transport viral process protein sumoylation viral transcription gene silencing by RNA negative regulation of epidermal growth factor receptor signaling pathway regulation of protein import into nucleus negative regulation of apoptotic process negative regulation of programmed cell death positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of MAP kinase activity positive regulation of epidermal growth factor receptor signaling pathway positive regulation of transcription, DNA-templated regulation of Ras protein signal transduction negative regulation of Ras protein signal transduction protein heterotrimerization ribonucleoprotein complex export from nucleus intracellular transport of virus regulation of cellular response to heat protein transport mRNA transport transport cell migration
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