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NUP85 Polyclonal Antibody

NUP85 Antibody in Immunocytochemistry (ICC/IF)

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NUP85 Antibody (19370-1-AP) in ICC/IF

IF result (Nucleus stain) of anti-NUP85 (19370-1-AP; 1:50) hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim.

NUP85 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

19370-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 2 publications 2 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NUP85 Fusion Protein Ag7086 (307-656 aa encoded by BC000697)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.16 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: FLVTRLLYS NPTVKPIDLH YYAQSSLDLF LGGESSPEPL DNILLAAFEF DIHQVIKECS IALSNWWFVA HLTDLLDHCK LLQSHNLYFG SNMREFLLLE YASGLFAHPS LWQLGVDYFD YCPELGRVSL ELHIERIPLN TEQKALKVLR ICEQRQMTEQ VRSICKILAM KAVRNNRLGS ALSWSIRAKD AAFATLVSDR FLRDYCERGC FSDLDLIDNL GPAMMLSDRL TFLGKYREFH RMYGEKRFAD AASLLLSLMT SRIAPRSFWM TLLTDALPLL EQKQVIFSAE QTYELMRCLE DLTSRRPVHG ESDTEQLQDD DIETTKVEML RLSLARNLAR AIIREGSLEG S (307-656 aa encoded by BC000697)

Target Information

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP85 is part of one such subcomplex, Nup107-160.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Case report: Compound heterozygous NUP85 variants cause autosomal recessive primary microcephaly.

Frontiers in neurology

Ravindran E,Lesca G,Januel L,Goldgruber L,Dickmanns A,Margot H,Kaindl AM

Tue Feb 28 00:00:00 UTC 2023

Nucleoporin 85 interacts with influenza A virus PB1 and PB2 to promote its replication by facilitating nuclear import of ribonucleoprotein.

Frontiers in microbiology

Ling YH,Wang H,Han MQ,Wang D,Hu YX,Zhou K,Li Y

Wed Sep 07 00:00:00 UTC 2022

Nucleoporin 85 interacts with influenza A virus PB1 and PB2 to promote its replication by facilitating nuclear import of ribonucleoprotein.

Frontiers in microbiology

Ling YH,Wang H,Han MQ,Wang D,Hu YX,Zhou K,Li Y

Wed Sep 07 00:00:00 UTC 2022

DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity.

Oncogene

Chen B,Xu F,Gao Y,Hu G,Zhu K,Lu H,Xu A,Chen S,Wu L,Zhao G

Tue Mar 01 00:00:00 UTC 2022

The mechanism of acentrosomal spindle assembly in human oocytes.

Science (New York, N.Y.)

Wu T,Dong J,Fu J,Kuang Y,Chen B,Gu H,Luo Y,Gu R,Zhang M,Li W,Dong X,Sun X,Sang Q,Wang L

Fri Nov 18 00:00:00 UTC 2022

Expanding the phenotype of NUP85 mutations beyond nephrotic syndrome to primary autosomal recessive microcephaly and Seckel syndrome spectrum disorders.

Human molecular genetics

Ravindran E,Jühlen R,Vieira-Vieira CH,Ha T,Salzberg Y,Fichtman B,Luise-Becker L,Martins N,Picker-Minh S,Bessa P,Arts P,Jackson MR,Taranath A,Kamien B,Barnett C,Li N,Tarabykin V,Stoltenburg-Didinger G,Harel A,Selbach M,Dickmanns A,Fahrenkrog B,Hu H,Scott H,Kaindl AM

Mon Nov 01 00:00:00 UTC 2021

Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses.

Genomics, proteomics & bioinformatics

Shi R,Feng Z,Zhang X

Fri Oct 01 00:00:00 UTC 2021

Efficient delivery of small interfering RNAs targeting particular mRNAs into pancreatic cancer cells inhibits invasiveness and metastasis of pancreatic tumors.

Oncotarget

Taniuchi K,Yawata T,Tsuboi M,Ueba T,Saibara T

Tue Apr 23 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: 85 kDa nucleoporin; FLJ12549; FROUNT; Nuclear pore complex protein Nup85; nucleoporin 85kDa; Nucleoporin Nup75; Nucleoporin Nup85; PCN; PCNT; Pericentrin-1

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Gene Aliases: FROUNT; NUP75; NUP85; PCNT1

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UniProt ID: (Human) Q9BW27, (Mouse) Q8R480

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Entrez Gene ID: (Human) 79902, (Mouse) 445007

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Function(s)

protein binding structural constituent of nuclear pore CCR2 chemokine receptor binding

Process(es)

transport chemotaxis protein transport cytokine-mediated signaling pathway lamellipodium assembly macrophage chemotaxis mRNA transport mRNA export from nucleus tRNA export from nucleus protein import into nucleus sister chromatid cohesion mitotic nuclear envelope disassembly regulation of glucose transport viral process protein sumoylation viral transcription gene silencing by RNA positive regulation of transcription, DNA-templated intracellular transport of virus regulation of cellular response to heat

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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NUP85 Polyclonal Antibody

NUP85 Antibody (19370-1-AP) in ICC/IF

Product Details

19370-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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